Dendritic polymers are recognized as the fourth and most recent new major macromolecular architecture. Dendrimers are a subclass of nanoscale, core-shell type dendritic polymers. They may be precisely and systematically controlled as a function of (a) size - number of shells (generations) surrounding the core, (b) shape (determined by core) and (c) surface chemistry (functional groups on the last shell). Presently, over 50 different interior compositions and over 200 different surface modifications are known. As such, they are perhaps the most versatile nanoscale building blocks available, however, they are somewhat less well known than the famous bucky balls and fullerene nanotubes. In this lecture,we wish to report the synthesis and characterization of a new class of dendrimers based on the synthetic hybridization of interior compositions derived from two commercially available dendrimers; namely, poly(amidoamine) (PAMAM) dendrimers (Dow Chemical Co.) and poly(propyleneimine) (PPI) dendrimers (DSM). The resulting "dendrimer copolymers" consist of (PPI) cores surrounded by (PAMAM) shells; thus, providing structure controlled nanoscale modules manifesting completely new properties for the construction of nanodevices.
Istvan J. Majoros, Sr. Polymer Chemist
University of Michigan Center for Biologic Nanotechnology
4027 Kresge Research Building II, 200 Zina Pitcher Place
Ann Arbor, MI 48109-0533 USA