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Archive for the 'Molecular Nanotechnology' Category

DNA nanotechnology provides new ways to arrange nanoparticles into crystal lattices

Posted by Jim Lewis on February 19th, 2016

Two research teams present two different methods for using single strands of DNA to link various nanoparticles into complex 3D arrays: one using DNA hairpins for dynamic reconfiguration and the other using a DNA origami scaffold.

DNA nanotechnology cages localize and optimize enzymatic reactions

Posted by Jim Lewis on February 16th, 2016

Encapsulating enzymes in nanocages engineered using structural DNA nanotechnology increases enzymatic digestion and protects enzymes from degradation.

Multiple advances in de novo protein design and prediction

Posted by Jim Lewis on February 14th, 2016

New families of protein structures, barrel proteins for positioning small molecules, self-assembling protein arrays, and precision sculpting of protein architectures highlight de novo protein design advances.

Rational design of protein architectures not found in nature

Posted by Jim Lewis on February 11th, 2016

Computational design of proteins satisfying predetermined geometric constraints produced stable proteins with the designed structure that are not found in nature.

De novo protein design space extends far beyond biology

Posted by Jim Lewis on February 3rd, 2016

A fully automated design protocol generates dozens of designs for proteins based on helix-loop-helix-loop repeat units that are very stable, have crystal structures that match the design, have very different overall shapes, and are unrelated to any natural protein.

Conference video: Nanoscale Materials, Devices, and Processing Predicted from First Principles

Posted by Jim Lewis on January 15th, 2016

Prof. William Goddard presented four advances from his research group that enable going from first principles quantum mechanics calculations to realistic nanosystems of interest with millions or billions of atoms.

DNA nanotechnology controls which molecules enter cells

Posted by Jim Lewis on January 13th, 2016

DNA building blocks mimic biological ion channels to more precisely control which molecules can cross a biological membrane.

Molecular arm grabs, transports, releases molecular cargo

Posted by Jim Lewis on January 12th, 2016

A molecular robotic arm synthesized from small synthetic organic molecules uses cyclic changes in pH and other reaction conditions to grab and release a cargo molecule, and swing the cargo back and forth between the two ends of the molecular platform.

Inexpensive transparent conductors from correlated metal nanostructures

Posted by Jim Lewis on January 6th, 2016

Highly correlated electron motions resembling electron liquids rather than electron gases, and found in some transition metal oxides, may enable inexpensive substitution for expensive displays.

Using DNA nanotechnology to position molecules with atomic precision

Posted by Jim Lewis on December 9th, 2015

German researchers have used scaffolded DNA origami to adjust the angle of a DNA hinge joint by altering the length of special “adjuster helices”, causing molecules attached to the sides of the hinge to be displaced by as little as 0.04 nm.

Single-molecule light-driven nanosubmarine

Posted by Jim Lewis on December 5th, 2015

Each time a laser pulse actuates the cis-trans isomerization of a single carbon-carbon double bond, a single-molecule nanosubmarine made of 244 atoms is driven forward 9 nm against Brownian diffusion.

Architecture for atomically precise quantum computer in silicon

Posted by Jim Lewis on November 9th, 2015

Building on previous work on single atom transistors and single atom qubits, Australian researchers have incorporated a quantum error correction code to make possible a scalable 3D silicon chip architecture that could lead to operational quantum computers.

One-directional rotation in a new artificial molecular motor

Posted by Jim Lewis on November 5th, 2015

Independent rotation of two wheels attached to either end of an axle has been achieved in a light-driven artificial molecular motor, suggesting a basis for a nanometer-scale transport system.

DNA nanomachine lights up to diagnose diseases

Posted by Jim Lewis on November 2nd, 2015

DNA nanotechnology produces an artificial molecular machine that changes shape when it encounters a specific antibody or other protein molecule, and emits light to signal the target’s presence.

Chirality-assisted synthesis a new tool for nanotechnology

Posted by Jim Lewis on October 30th, 2015

A novel application of supramolecular chemistry allows molecules to join in only one direction, providing a new way to control the shape of large molecules.

Surface assisted self-assembly of DNA origami nanostructures

Posted by Jim Lewis on October 26th, 2015

A lipid bilayer supported by a mica surface assisted the mobile self-assembly of DNA nanostructures of various shapes into micrometer-scale 2D lattices.

Free online edition of The Feynman Lectures on Physics

Posted by Jim Lewis on October 25th, 2015

A free to read online edition of the classic 3-volume physics text developed from Richard Feynman’s legendary Cal Tech physics lectures, specially designed for online reading, has been made available by the California Institute of Technology and the Feynman Lectures Website.

Conference video: New Methods of Exploring, Analyzing, and Predicting Molecular Interactions

Posted by Jim Lewis on October 8th, 2015

Prof. Art Olson discussed how we understand what we cannot see directly, how we integrate data from different sources, and how to develop software tools to move forward.

Foresight co-founder on the future of the human lifespan

Posted by Jim Lewis on October 6th, 2015

Optimized Geek podcast featured Christine Peterson on the future of nanotechnology, human lifespan, artificial intelligence, finding love, and other topics.

DNA nanotechnology guides assembling cells into 'Organoids'

Posted by Jim Lewis on September 30th, 2015

DNA strands decorating cell membranes like ‘Velcro’ program the adhesion of cells to other cells or to extracellular matrices to build tiny tissue models.