Nanoparticles made from specific DNA and RNA strands, homogeneous in size, composition, and surface chemistry, proved superior to other nanoparticles in silencing gene expression in tumors in mouse experiments.
Archive for the 'Molecular Nanotechnology' Category
A theoretical study shows that although thermal noise cannot be used to produce useful motion by mesoscale or macroscale machines, it can be used by nanoscale machines without violating the second law of thermodynamics.
The demonstration that the process of DNA replication is more flexible than thought should make it easier to incorporate unusual amino acids into designed proteins, which might make it easier to design novel protein machines.
Tryptophan residues introduced at various positions in a protein chain identify folding intermediates that are too short-lived to be structurally characterized otherwise.
A variety of protein cage structures have been constructed by designing specific protein domains to self-assemble as atomically precise protein building blocks in defined geometries.
A set of 310 short single-stranded DNA tiles, plus a few additional short sequences for the edges, has been used to form more than a hundred large, complex DNA objects.
Darpa has launched a “Living Foundries” program to bring an engineering perspective to synthetic biology to greatly accelerate progress through standardization and modularization.
Recent interview touches on new Foresight programs and issues in nanotechnology development
Calculations using density functional theory have demonstrated that graphene can be made piezoelectric by adsorbing atoms or molecules on one surface, or by adsorbing different atoms or molecules on each surface.
Creating a superlattice by placing graphene on boron nitride may allow control of electron motion in graphene and make graphene electronics practical.
A set of rationally engineered transcriptional regulators for yeast will make it easier to build complex molecular machine systems in yeast, some of which may become useful additions to pathway technologies for atomically precise manufacturing and productive nanosystems.
A combination of a molecular motor protein and a nanopore protein has been harnessed for rapidly sequencing single DNA molecules.
Functioning DNA nanorobots to deliver specific molecular signals to cells were designed by combining DNA origami, DNA aptamers, and DNA logic gates.
A talk at TEDxBerkeley includes nanotechnology among the options for digital fabrication, one of five new rules of innovation.
New computational methods to explore the rapidly expanding collection of high resolution three-dimensional RNA structures reveal new RNA structural motifs, identifying additional building blocks for complex RNA nanostructures.
A set of machine learning programs can now predict properties of small organic molecules as accurately as can calculations based upon the Schrödinger equation, but in milliseconds rather than hours.
Researchers in Australia and the US have demonstrated a working transistor by placing of single atom of phosphorous with atomic precision between gates made of wires only a few phosphorous atoms wide. This demonstration points to possibly extending current computer technology to the atomic scale.
A field-effect tunneling transistor comprising a vertical heterostructure of atomically thin layers of graphene and boron nitride or molybdenum disulfide may pave the way for computer chips based on graphene nanotechnology.
Scientists at Kyoto University and the University of Oxford have combined DNA origami and DNA motors to take another step toward programmed artificial molecular assembly lines.
Foldit game players have again out-performed scientists in protein design, this time improving the design of a protein designed from scratch to catalyze Diels-Alder cycloadditions.