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Archive for the 'Molecular Nanotechnology' Category

Atomically precise nanoparticle provides better drug delivery

Posted by Jim Lewis on July 10th, 2012

Nanoparticles made from specific DNA and RNA strands, homogeneous in size, composition, and surface chemistry, proved superior to other nanoparticles in silencing gene expression in tumors in mouse experiments.

Nanomachines and molecular motors can make use of thermal noise

Posted by Jim Lewis on July 3rd, 2012

A theoretical study shows that although thermal noise cannot be used to produce useful motion by mesoscale or macroscale machines, it can be used by nanoscale machines without violating the second law of thermodynamics.

An expanded genetic alphabet could lead to more easily designed proteins

Posted by Jim Lewis on June 22nd, 2012

The demonstration that the process of DNA replication is more flexible than thought should make it easier to incorporate unusual amino acids into designed proteins, which might make it easier to design novel protein machines.

New method to identify intermediates in protein folding

Posted by Jim Lewis on June 12th, 2012

Tryptophan residues introduced at various positions in a protein chain identify folding intermediates that are too short-lived to be structurally characterized otherwise.

Advancing nanotechnology with protein building blocks

Posted by Jim Lewis on June 6th, 2012

A variety of protein cage structures have been constructed by designing specific protein domains to self-assemble as atomically precise protein building blocks in defined geometries.

DNA tiles provide faster, less expensive way to fabricate complex DNA objects

Posted by Jim Lewis on May 31st, 2012

A set of 310 short single-stranded DNA tiles, plus a few additional short sequences for the edges, has been used to form more than a hundred large, complex DNA objects.

New Darpa program may accelerate synthetic biology path to advanced nanotechnology

Posted by Jim Lewis on May 26th, 2012

Darpa has launched a “Living Foundries” program to bring an engineering perspective to synthetic biology to greatly accelerate progress through standardization and modularization.

Foresight Institute on Singularity Hub (video)

Posted by Jim Lewis on May 12th, 2012

Recent interview touches on new Foresight programs and issues in nanotechnology development

Will piezoelectric graphene provide options for nanoscale manipulation?

Posted by Jim Lewis on April 25th, 2012

Calculations using density functional theory have demonstrated that graphene can be made piezoelectric by adsorbing atoms or molecules on one surface, or by adsorbing different atoms or molecules on each surface.

Mounting graphene on boron nitride improves its electronic properties

Posted by Jim Lewis on April 21st, 2012

Creating a superlattice by placing graphene on boron nitride may allow control of electron motion in graphene and make graphene electronics practical.

Adding to the toolbox for making complex molecular machines

Posted by Jim Lewis on April 4th, 2012

A set of rationally engineered transcriptional regulators for yeast will make it easier to build complex molecular machine systems in yeast, some of which may become useful additions to pathway technologies for atomically precise manufacturing and productive nanosystems.

Nanotechnology-based sensor does rapid reads of single DNA molecule

Posted by Jim Lewis on April 1st, 2012

A combination of a molecular motor protein and a nanopore protein has been harnessed for rapidly sequencing single DNA molecules.

DNA nanotechnology-based nanorobot delivers cell suicide message to cancer cells

Posted by Jim Lewis on March 8th, 2012

Functioning DNA nanorobots to deliver specific molecular signals to cells were designed by combining DNA origami, DNA aptamers, and DNA logic gates.

Nanotechnology, digital fabrication, and innovation at TED

Posted by Jim Lewis on March 2nd, 2012

A talk at TEDxBerkeley includes nanotechnology among the options for digital fabrication, one of five new rules of innovation.

Novel RNA structural motifs expand tool kit for RNA nanotechnology

Posted by Jim Lewis on February 26th, 2012

New computational methods to explore the rapidly expanding collection of high resolution three-dimensional RNA structures reveal new RNA structural motifs, identifying additional building blocks for complex RNA nanostructures.

Machine learning may improve molecular design for nanotechnology

Posted by Jim Lewis on February 22nd, 2012

A set of machine learning programs can now predict properties of small organic molecules as accurately as can calculations based upon the Schrödinger equation, but in milliseconds rather than hours.

Atomically-precise positioning of a single atom transistor-VIDEO

Posted by Jim Lewis on February 19th, 2012

Researchers in Australia and the US have demonstrated a working transistor by placing of single atom of phosphorous with atomic precision between gates made of wires only a few phosphorous atoms wide. This demonstration points to possibly extending current computer technology to the atomic scale.

Graphene heterostructures may lead to graphene-based computer chips

Posted by Jim Lewis on February 12th, 2012

A field-effect tunneling transistor comprising a vertical heterostructure of atomically thin layers of graphene and boron nitride or molybdenum disulfide may pave the way for computer chips based on graphene nanotechnology.

DNA motor navigates network of DNA tracks

Posted by Jim Lewis on January 31st, 2012

Scientists at Kyoto University and the University of Oxford have combined DNA origami and DNA motors to take another step toward programmed artificial molecular assembly lines.

Crowd-sourced protein design a promising path to advanced nanotechnology

Posted by Jim Lewis on January 24th, 2012

Foldit game players have again out-performed scientists in protein design, this time improving the design of a protein designed from scratch to catalyze Diels-Alder cycloadditions.