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Archive for the 'Research' Category

Scaffolded DNA origami improvements advance DNA nanotechnology

Posted by Jim Lewis on September 25th, 2014

A 10-fold larger breadboard and 350-fold lower DNA synthesis costs make DNA origami a more useful stepping-stone toward atomically precise manufacturing.

Novel multifunctional nanoparticle for diagnosis and therapy

Posted by Jim Lewis on September 14th, 2014

A nanoparticle that self-assembles from porphyrin, cholic acid, amino acids, and polyethylene glycol is a promising vehicle for delivering both imaging agents and cancer drugs to tumors.

Proof of principle for nanoscale assembly line

Posted by Jim Lewis on September 2nd, 2014

Swiss researchers have used biomolecular shuttles to capture molecular building blocks from solution and transport them across fluid flow boundaries to be further manipulated in a subsequent chamber.

Seeing and touching a single synthetic molecular machine

Posted by Jim Lewis on August 24th, 2014

Attaching a 200-nm-diameter magnetic bead to a 1-nm diameter synthetic molecular machine allowed optical visualization of the motion of the machine and manipulation with a magnetic tweezers.

Tunable Assembly of Nanoparticles for (Photovoltaic) Devices

Posted by Stephanie C on August 13th, 2014

Photovoltaics are an interesting case where atomic precision is not necessary to achieve potentially dramatic global impacts. Even an “ok efficiency” device that is easy to manufacture with reduced environmental hazard could have significant beneficial effects on energy resources and on device fabrication processes (which could, in turn, contribute to developments toward APM). The struggle [...]

Nanotechnology-based next generation memory nears mass production

Posted by Jim Lewis on August 10th, 2014

Rice University’s breakthrough nanoporous silicon oxide technology for resistive random-access memory (RRAM) appears poised for commercialization.

The atomically precise manufacture of quantum dots

Posted by Jim Lewis on July 5th, 2014

Using an STM to precisely position indium adatoms on an indium arsenide surface, nanotechnologists have created a series of atomically precise quantum dots, and joined them with atomic precision to make quantum dot molecules, opening new avenues to construct practical quantum devices for computing and other applications.

Lipid coat protects DNA nanorobot from immune attack

Posted by Jim Lewis on July 5th, 2014

Enveloped DNA nanostructures were developed to escape attacks from nucleases and the immune system, opening a path to ever more sophisticated DNA nanomedical devices.

Robust triangular RNA brick adds to RNA nanotechnology toolkit

Posted by Jim Lewis on June 24th, 2014

The complex molecular recognition code of RNA offers RNA nanotechnology a greater variety of 3D structures and functions than are present in DNA nanotechnology, but the RNA structures can be fragile. New RNA triangles that resist boiling solve this problem.

Novel properties for nanotechnology rebar-graphene reinforced with carbon nanotubes

Posted by Jim Lewis on June 9th, 2014

Carbon-containing functional groups decorating carbon nanotubes decompose upon heating on copper foil to form a nanotube-reinforced graphene with novel properties that mimic those of expensive indium-tin-oxide.

DNA nanotechnology replicates enzyme cascade

Posted by Jim Lewis on June 4th, 2014

A swinging DNA arm added to a DNA scaffold makes it possible for two enzymes attached to the scaffold to complete a coupled chemical reaction.

Expanded DNA alphabet provides more options for nanotechnology

Posted by Jim Lewis on May 14th, 2014

A bacterium has been engineered to stably propagate a DNA written with six letters instead of the usual four, greatly expanding the number of amino acids, both natural and synthetic, that can be genetically encoded. Further work could lead to novel proteins incorporating these additional amino acids, and from there to novel materials, devices, and machines.

Nanotechnology to provide efficient, inexpensive water desalination

Posted by Jim Lewis on May 12th, 2014

Two different nanotechnology-based approaches to use graphene as the basis for purification and desalination of water look promising.

Nanotechnology to provide better solar cells, optical devices

Posted by Jim Lewis on May 9th, 2014

A novel method to control the configuration of atoms in semiconductors grown on graphene will make possible a vast array of new optical devices, including better solar cells.

To fight inflammation nanoparticles turn 'naughty' neutrophils into 'nice' neutrophils

Posted by Jim Lewis on May 1st, 2014

By targeting the protein that attaches a type of immune cell called neutrophils to blood vessel walls where they cause serious tissues damage, the neutrophils are released and returned to the circulation to resume their normal functions.

Novel nanoparticle efficiently silences gene expression in liver cells

Posted by Jim Lewis on April 29th, 2014

RNA interference provides potential cures for various diseases by silencing the expression of specific genes in specific organs, but delivering the RNA molecules to the right place is very difficult. A novel nanoparticle provides unprecedented efficiency in silencing target genes in liver cells.

Physicists suppress 'stiction' force that bedevils microscale machinery

Posted by Jim Lewis on April 19th, 2014

A possible top-down path to atomically precise manufacturing that passes through microscale machinery might be rendered easier because of recent progress in suppressing the Casimir force, which contributes to the ‘stiction’ problem often encountered with microelectromechanical systems.

Programmable nanoprocessors integrated into a nanowire nanocomputer

Posted by Jim Lewis on March 30th, 2014

Pioneering a design and fabrication strategy to address individual nanoscale electronic devices to enable large-scale assembly into integrated computer circuits, a MITRE-Harvard team has assembled a functional nanoelectronic control computer.

Bigger, stiffer, roomier molecular cages from structural DNA nanotechnology

Posted by Jim Lewis on March 29th, 2014

Using struts made of DNA to stiffen polyhedral corners, scientists have build rigid DNA cages an order of magnitude larger than previous DNA nanostructures, and only one order of magnitude smaller than bacterial cells.

Chemists provide new tool for nanotechnology-modifying the right carbon atom

Posted by Jim Lewis on March 27th, 2014

A new tool to chemically modify one specific carbon atom among several chemically very similar ones will facilitate building larger, more complex molecules for drug discovery and for nanotechnology.