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Archive for the 'Research' Category

Electron tomography reveals precise positions of individual atoms in aperiodic material

Posted by Jim Lewis on January 11th, 2016

The positions of 3769 tungsten atoms in a tungsten needle segment were determined to a precision of 19 pm (0.019 nm), including the position of a single atom defect in the interior of the sample, by using aberration-corrected scanning transmission electron microscopy and computerized tomography.

Nanoparticles ameliorate MS in mice by inducing immune tolerance of myelin

Posted by Jim Lewis on January 7th, 2016

In the first mouse model of the progressive form of multiple sclerosis, nanoparticles that created immune tolerance to myelin prevented the development of progressive MS.

Inexpensive transparent conductors from correlated metal nanostructures

Posted by Jim Lewis on January 6th, 2016

Highly correlated electron motions resembling electron liquids rather than electron gases, and found in some transition metal oxides, may enable inexpensive substitution for expensive displays.

Active and reversible control of nanoparticle optical properties

Posted by Jim Lewis on January 3rd, 2016

Electrochemically modifying individual metallic nanoparticles and pairs of such nanoparticles enabled reversible tuning of their optical properties, including charge transfer plasmon formation in nanoparticle pairs.

Rolling DNA-based motors increase nano-walker speeds 1000-fold

Posted by Jim Lewis on December 12th, 2015

Coating micrometer-sized glass spheres with hundreds of DNA strands complementary to an RNA covering a glass slide enables the sphere to move, with the help of an enzyme that digests RNA bound to complementary DNA, a thousand times faster than conventional DNA-walkers.

Octopodal nanoparticles combine catalytic, plasmonic functions

Posted by Jim Lewis on December 11th, 2015

Eight-armed nanoparticles of gold coated with a gold-palladium alloy proved to be both efficient plasmonic sensors and efficient catalysts, even though gold alone is not normally a good catalyst and palladium is a poor plasmonic material.

Novel nanoconjugate delivers synergistic combination of microRNAs to treat cancer

Posted by Jim Lewis on December 11th, 2015

Two microRNAs with synergistic effects, one that suppresses tumor growth and another than inhibits tumor promotion, are combined in an RNA triple helix, complexed with a dendrimer to form nanoparticles, which are incorporated with a polymer to form a hydrogel that inhibits tumor growth when applied to the tumor.

Ultrasensitive microRNA assay with nanosensor to detect cancer

Posted by Jim Lewis on December 10th, 2015

A nanotechnology-based sensor provides fast, inexpensive, ultrasensitive assay of microRNA pattern to detect cancer using DNA immobilized on a synthetic gold nanoprism.

Using DNA nanotechnology to position molecules with atomic precision

Posted by Jim Lewis on December 9th, 2015

German researchers have used scaffolded DNA origami to adjust the angle of a DNA hinge joint by altering the length of special “adjuster helices”, causing molecules attached to the sides of the hinge to be displaced by as little as 0.04 nm.

Single-molecule light-driven nanosubmarine

Posted by Jim Lewis on December 5th, 2015

Each time a laser pulse actuates the cis-trans isomerization of a single carbon-carbon double bond, a single-molecule nanosubmarine made of 244 atoms is driven forward 9 nm against Brownian diffusion.

Atomic precision in sculpting 3-D objects

Posted by Jim Lewis on December 3rd, 2015

Nanometer-level control of the beam path of a scanning transmission electron microscope nudges an amorphous material into atomically precise epitaxial growth.

Generating hydrogen with single atom catalysts

Posted by Jim Lewis on November 13th, 2015

Single cobalt atoms have been positioned in nitrogen-doped graphene to catalytically produce hydrogen from water almost as effectively as using vastly more expensive platinum catalysts.

Architecture for atomically precise quantum computer in silicon

Posted by Jim Lewis on November 9th, 2015

Building on previous work on single atom transistors and single atom qubits, Australian researchers have incorporated a quantum error correction code to make possible a scalable 3D silicon chip architecture that could lead to operational quantum computers.

One-directional rotation in a new artificial molecular motor

Posted by Jim Lewis on November 5th, 2015

Independent rotation of two wheels attached to either end of an axle has been achieved in a light-driven artificial molecular motor, suggesting a basis for a nanometer-scale transport system.

DNA nanomachine lights up to diagnose diseases

Posted by Jim Lewis on November 2nd, 2015

DNA nanotechnology produces an artificial molecular machine that changes shape when it encounters a specific antibody or other protein molecule, and emits light to signal the target’s presence.

Chirality-assisted synthesis a new tool for nanotechnology

Posted by Jim Lewis on October 30th, 2015

A novel application of supramolecular chemistry allows molecules to join in only one direction, providing a new way to control the shape of large molecules.

Surface assisted self-assembly of DNA origami nanostructures

Posted by Jim Lewis on October 26th, 2015

A lipid bilayer supported by a mica surface assisted the mobile self-assembly of DNA nanostructures of various shapes into micrometer-scale 2D lattices.

Conference video: New Methods of Exploring, Analyzing, and Predicting Molecular Interactions

Posted by Jim Lewis on October 8th, 2015

Prof. Art Olson discussed how we understand what we cannot see directly, how we integrate data from different sources, and how to develop software tools to move forward.

Nanotechnology carries gene editing package into cells

Posted by Jim Lewis on October 2nd, 2015

Hijacking a viral method of replicating circular genomes, ball-of-yarn-like DNA clews are used to transport the protein and guide RNA molecules needed for gene editing into the cell nucleus.

DNA nanotechnology guides assembling cells into 'Organoids'

Posted by Jim Lewis on September 30th, 2015

DNA strands decorating cell membranes like ‘Velcro’ program the adhesion of cells to other cells or to extracellular matrices to build tiny tissue models.