A review from the group leading recent rapid progress in de novo protein design describes the successes, identifies the remaining challenges, and heralds the advance “from the Stone Age to the Iron Age” in protein design.
Archive for the 'Reviews' Category
Increasing efficiency and utilization and lowering costs for harvesting, converting, transporting, and storing energy produced from sunlight provides a showcase for a variety of nanoscale materials, structures, and processes.
Polymer chemistry and materials research provide opportunities to explore structures that harmonize phenomena unique to nanoscale technology, the role of mechanical forces generated at interfaces, and the responses of biological systems to mechanical stresses.
A molecular robotic arm synthesized from small synthetic organic molecules uses cyclic changes in pH and other reaction conditions to grab and release a cargo molecule, and swing the cargo back and forth between the two ends of the molecular platform.
An extensive review of artificial molecular machines, their large-amplitude motions, and the changes these motions produce, emphasizes small molecules and the central role of chemistry in their design and operation.
Simple molecular switches based upon bistable mechanically interlocked molecules can be incorporated within pre-assembled metal organic frameworks and addressed electrochemically.
A review of molecular parts that act as switches, motors, and ratchets illuminates similarities between artificial and biological molecular machines and argues that useful applications are coming.
A European Science and Technology Roadmap for Graphene, Related Two-Dimensional Crystals, and Hybrid Systems hints at the opportunities to be harvested from, and the need for, the development of atomically precise manufacturing (APM).
An overview of three decades of progress in DNA nanotechnology emphasizes bringing programmed motion to DNA nanostructures, including efforts to incorporate design principles from macroscopic mechanical engineering.
Reviewing Eric Drexler’s Radical Abundance, Phil Bowermaster provides an informed and insightful overview of the controversies that greeted the proposal for a nanotechnology aimed at developing a practical technology for atomically precise manufacturing. Along the way he shows how Drexler’s outlook evolved from 1986 to 2013.
A collection of open access journals on a variety of topics provides a very useful entry point to the rapidly growing collection of scientific, technical, and scholarly research that is not hidden behind pay walls.
A new book by Frank Boehm explores the challenges, possibilities, and visions of nanomedical device and systems design.
Two open access reviews portray the widening approach of DNA nanotechnology toward more complex atomically precise systems.
A brief article reviews several types of molecular machines that chemists have built to mimic biology and provide movement for future types of nanotechnology.
A tutorial review available after free registration presents a theory-based exploration of the difficulty in moving from simple molecular switches to arrays of artificial molecular machines capable to doing substantial, useful external work.
A tutorial review addresses the distinction between the many simple artificial molecular devices that are currently available and truly effective artificial molecular machines that would mimic the ubiquitous molecular machines present in living systems.
Those interested in issues of communication at the nanoscale will be interested to learn that the first volume of the new journal Nano Communication Networks, from Elsevier, edited by Ian Akyildiz, is available free of charge. The volume comprises four issues dated March through December of 2010. Just to pick one article out of dozens [...]
A new book collects the papers and discussions from the 2007 Solvay Conference “From Noncovalent Assemblies to Molecular Machines”.
RNA nanostructures chemically modified to be resistant to degradation retain 3D structure and biological activity.
Robert A. Freitas Jr. has made available his chapter on nanorobotics from the book The Future of Aging.