Gold nanoparticles densely coated with RNA molecules intended to silence a gene essential for an incurable brain cancer proved effective in mice engrafted with human glioblastoma multiforme tumor.
Archive for the 'Bionanotechnology' Category
Modifying DNA strands with lipid-like molecules opens more possibilities for designing DNA structures for drug delivery and other purposes.
A major advance in the computational design of proteins that bind tightly to specific small molecules will facilitate several technologies, possibly including the development of atomically precise manufacturing.
How complex could circuits be made using precisely positioned DNA nanostructures as templates to grow graphene nanoribbons?
“Molecular threading”, a nanotechnology developed by Halcyon Molecular and now owned by Aeon Biowares, enables precise placement of individual long molecules of DNA, either for sequencing or for nanofabrication of novel DNA nanostructures.
The Conference to be held February 7-9, 2014 in Palo Alto, California will emphasize the integration of nano-engineered devices and materials into larger, more complex systems.
In simplest terms, cellular automata can be thought of as groups of ‘cells’ in which the state of an individual cell will flip depending on the states of its neighbors. A ‘cell’ can be a pixel, a molecule, etc. The mathematical rules associated with cellular automation are complex and have been applied to fields as [...]
Good old fashioned boxes are here to stay, even in the context of nanoscale devices. Across a broad range of technologies and size regimes, boxes serve as containers for components, barriers against contaminants and/or radiation, and, as in the case of cell membranes, can be permeable to allow selected interactions between the interior and exterior. [...]
A pillar constructed and positioned using DNA nanotechnology holds two gold nanoparticles and a dye molecule to enhance fluorescence over a hundred fold.
Two open access reviews portray the widening approach of DNA nanotechnology toward more complex atomically precise systems.
A simple DNA scaffold organizes light-collecting molecules for artificial photosynthesis.
Biotechnology-based isolation and amplification of sequence-verified clones of DNA oligonucleotides will provide longer and less expensive materials for building complex DNA nanostructures and nanomachinery.
Revolution of DNA around a central channel, rather than rotation, is the method used by a viral molecular motor to package DNA. A structure facilitating bottom-up assembly may lead to roles in nanotechnology for these nanomotors.
In anticipation of Eric Drexler’s new book, Forbes contributor Bruce Dorminey interviews him about the meaning of nanotechnology and its revolutionary prospects. Selected excerpt: … In what fields would APM cause the most pronounced economic disruption and the collapse of global supply chains to more local chains? The digital revolution had far-reaching effects on information [...]
By forcing the geometry of the junctions upon which DNA nanotechnology depends, researchers have increased the collection of 2D and 3D structures that they can build to include wire frames and mesh structures.
Nanoparticles decorated to avoid immune system recognition were tested in mice and shown to survive longer and deliver more imaging dye and drug to tumor cells.
In this Forbes interview, contributor John Nosta introduces us to a teen worth watching: fifteen-year-old Jack Andraka, whose effort to design a nanotube-based sensor for pancreatic cancer detection was initially ignored. The interview taps into some aspects of how innovation occurs and the challenges of bringing new ideas to fruition – aspects which transcend age, [...]
A proposed large project to produce a dynamic map of the functional connectome of the human brain will require a convergence of neuroscience, biotechnology, nanotechnology, and computation, and may therefore spur the development of advanced nanotechnology leading to molecular manufacturing.
Core-shell nanocapsules deliver a potent protein complex to the nucleus of cancer cells where it induces them to commit suicide, while the complex degrades harmlessly in the cytoplasm of normal cells.
In a 47-minute interview Christine Peterson discusses the future that science and technology is bringing over the next few decades, and how to get involved to push the future in a positive direction.