Foresight Nanotech Institute Logo
Image of nano

Archive for the 'Bionanotechnology' Category

Nanoscale box aids single-molecule optical detection

Posted by Stephanie C on July 29th, 2013

Good old fashioned boxes are here to stay, even in the context of nanoscale devices. Across a broad range of technologies and size regimes, boxes serve as containers for components, barriers against contaminants and/or radiation, and, as in the case of cell membranes, can be permeable to allow selected interactions between the interior and exterior. [...]

DNA nanotechnology positions components to optimize single-molecule fluorescence

Posted by Jim Lewis on July 19th, 2013

A pillar constructed and positioned using DNA nanotechnology holds two gold nanoparticles and a dye molecule to enhance fluorescence over a hundred fold.

Reviews of DNA nanotechnology-atomically precise microscale objects

Posted by Jim Lewis on July 9th, 2013

Two open access reviews portray the widening approach of DNA nanotechnology toward more complex atomically precise systems.

DNA nanotechnology builds solar energy antenna

Posted by Jim Lewis on June 21st, 2013

A simple DNA scaffold organizes light-collecting molecules for artificial photosynthesis.

Mass production of higher quality oligonucleotides to spur DNA nanotechnology

Posted by Jim Lewis on June 6th, 2013

Biotechnology-based isolation and amplification of sequence-verified clones of DNA oligonucleotides will provide longer and less expensive materials for building complex DNA nanostructures and nanomachinery.

RNA-protein motor for unidirectional movement of DNA in nanomachinery

Posted by Jim Lewis on April 1st, 2013

Revolution of DNA around a central channel, rather than rotation, is the method used by a viral molecular motor to package DNA. A structure facilitating bottom-up assembly may lead to roles in nanotechnology for these nanomotors.

Nanotechnology revolution: An interview with Eric Drexler

Posted by Stephanie C on March 29th, 2013

In anticipation of Eric Drexler’s new book, Forbes contributor Bruce Dorminey interviews him about the meaning of nanotechnology and its revolutionary prospects. Selected excerpt: … In what fields would APM cause the most pronounced economic disruption and the collapse of global supply chains to more local chains? The digital revolution had far-reaching effects on information [...]

Re-engineering a junction to give a new twist to DNA nanotechnology

Posted by Jim Lewis on March 29th, 2013

By forcing the geometry of the junctions upon which DNA nanotechnology depends, researchers have increased the collection of 2D and 3D structures that they can build to include wire frames and mesh structures.

Computationally designed peptide sneaks nanoparticles past immune system

Posted by Jim Lewis on March 15th, 2013

Nanoparticles decorated to avoid immune system recognition were tested in mice and shown to survive longer and deliver more imaging dye and drug to tumor cells.

A teenager’s step toward nanomedicine innovation

Posted by Stephanie C on March 6th, 2013

In this Forbes interview, contributor John Nosta introduces us to a teen worth watching: fifteen-year-old Jack Andraka, whose effort to design a nanotube-based sensor for pancreatic cancer detection was initially ignored. The interview taps into some aspects of how innovation occurs and the challenges of bringing new ideas to fruition – aspects which transcend age, [...]

Proposed Brain Activity Map may also advance nanotechnology

Posted by Jim Lewis on March 1st, 2013

A proposed large project to produce a dynamic map of the functional connectome of the human brain will require a convergence of neuroscience, biotechnology, nanotechnology, and computation, and may therefore spur the development of advanced nanotechnology leading to molecular manufacturing.

Nanotechnology delivers potent anti-cancer agent where it needs to go

Posted by Jim Lewis on February 22nd, 2013

Core-shell nanocapsules deliver a potent protein complex to the nucleus of cancer cells where it induces them to commit suicide, while the complex degrades harmlessly in the cytoplasm of normal cells.

Christine Peterson on pushing the future in a positive direction

Posted by Jim Lewis on February 20th, 2013

In a 47-minute interview Christine Peterson discusses the future that science and technology is bringing over the next few decades, and how to get involved to push the future in a positive direction.

Christine Peterson interviewed on nanotechnology

Posted by Jim Lewis on February 12th, 2013

An interview with Foresight Co-Founder and Past President Christine Peterson covering both the current state and the future prospects of nanotechnology is available on Youtube.

Synthetic biology industrial revolution inspires hope for molecular manufacturing

Posted by Jim Lewis on February 2nd, 2013

A demonstration that most fundamental biological processes can be implemented in a test tube as efficiently as in live bacteria provides synthetic biology the tools to create a ‘new industrial revolution’, which may or may not lead to more general molecular manufacturing.

Testing and improving scaffolded DNA origami for molecular nanotechnology

Posted by Jim Lewis on December 19th, 2012

In two different sets of experiments a German research group has shown that scaffolded DNA origami can be used to assemble complex structures with precise sub-nanometer positional control, and that constant temperature reaction can greatly increase yields and decrease production times.

Optimal bond loads in designing molecular machines

Posted by Jim Lewis on December 11th, 2012

A study of a biological molecular machine has shown that the machine functions most effectively when it uses chemical bonds just barely strong enough to survive the power stroke of the machine.

Arbitrarily complex 3D DNA nanostructures built from DNA bricks

Posted by Jim Lewis on December 6th, 2012

A set of 32-nucleotide single strand DNA bricks was designed so that each can interact independently with four other DNA bricks so that sets of hundreds of bricks can self-assemble into arbitrarily complex 25-nm 3D shapes, each comprising 1000 8-base pair volume elements.

Nanotechnology milestone: general method for designing stable proteins

Posted by Jim Lewis on November 21st, 2012

Five proteins were designed from scratch and found to fold into stable proteins as designed, proving the ability to provide ideal, robust building blocks for artificial protein structures.

More complex circuits for synthetic biology lead toward engineered cells

Posted by Jim Lewis on November 6th, 2012

One possible pathway from current technology to advanced nanotechnology that will comprise atomically precise manufacturing implemented by atomically precise machinery is through adaptation and extension of the complex molecular machine systems evolved by biology. Synthetic biology, which engineers new biological systems and function not evolved in nature, is an intermediate stage along this path. An [...]