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Archive for the 'Productive Nanosystems' Category

New scaffold for nanotechnology engineered from amyloid-like proteins

Posted by Jim Lewis on April 4th, 2015

Design and computational simulation of amyloid proteins of diverse functions from diverse sources enable the self-assembly of proteins that could provide scaffolds for diverse applications.

Cotranscriptional folding of single RNA strand added to nanotechnology toolkit

Posted by Jim Lewis on March 31st, 2015

RNA origami brings new dimensions to nucleic acid nanotechnology by exploiting the much greater variety of RNA structural motifs (compared to DNA) to do what cannot easily be done with DNA origami, like fold into predetermined nanostructures rapidly while being transcribed.

Automated synthesis expands nanotechnology building block repertoire

Posted by Jim Lewis on March 24th, 2015

Iterative coupling, purification, and cyclization of a large collection of organic building blocks promises a vast array of complex small and medium sized molecules as candidates for drug discovery, catalysis, and nanotechnology.

Atomically precise manufacturing as the future of nanotechnology

Posted by Jim Lewis on March 8th, 2015

A commentary over at Gizmodo argues that ideas about molecular manufacturing that sounded like science fiction in 1986 now sound more like science fact.

Are nanorobots and atomically precise manufacturing becoming mainstream nanotechnology?

Posted by Jim Lewis on March 7th, 2015

The idea that nanorobots fabricated by atomically precise manufacturing processes are a likely part of our future, and that this is a good thing, is appearing more frequently, largely as a result of Drexler’s recent book Radical Abundance.

Structural DNA nanotechnology with programmed motions

Posted by Jim Lewis on January 28th, 2015

Scaffolded DNA origami is combined with hinges of single- or double-stranded DNA to built simple machines parts that have been combined to program simple to complex motions.

What sort of abundance will nanotechnology bring?

Posted by Jim Lewis on January 11th, 2015

One example is presented of how well the meme is spreading that nanotechnology will evolve toward atomically precise manufacturing that will in turn bring forth a world of abundance.

Swarms of DNA nanorobots execute complex tasks in living animal

Posted by Jim Lewis on January 6th, 2015

Combinations of different types of DNA nanorobots, implementing different logic gates, work together to tag a specific type of cell in a living cockroach depending on the presence or absence of two protein signals.

Computational framework for structural DNA nanotechnology

Posted by Jim Lewis on December 27th, 2014

A more general computational framework predicts the structures of 2D and 3D-curved DNA nanostructures impossible to predict using previously available computational methods. May lead to 3D-printing DNA nanostructures?

Broadening the synthetic biology path to molecular nanotechnology

Posted by Jim Lewis on December 6th, 2014

Advances in the de novo design of coiled-coil proteins made by two different research groups proceeding by two different routes demonstrate that the range of protein nanostructures potentially available for various molecular machine systems is significantly larger than the range of such structures already exploited by natural selection.

Grant program to support nanotechnology and other infrastructure

Posted by Jim Lewis on October 25th, 2014

The US National Science Foundation announced a new grant program to develop and apply next-generation networking to advance nanotechnology and other emerging technologies to meet important national needs.

Foresight Directed/Programmable Matter for Energy Workshop

Posted by Jim Lewis on October 10th, 2014

A small, interactive group of invited experts gathered in Palo Alto recently to discuss prospects for revolutionary advances in energy storage, transmission, and generation through nanotechnology.

A Breakthrough in 3D Imaging by EM Alone

Posted by Stephanie C on October 8th, 2014

The need for improved imaging and characterization on the nanoscale was emphasized in the 2007 Roadmap and again at the 2013 Foresight Conference on Atomic Precision. We noted last year a new advancement in atomic-scale resolution of 10-nm platinum particles, requiring multiple imaging techniques in combination, and recently the marked improvement in optical imaging for [...]

Tailoring the shapes of organic molecules by assembly-line synthesis

Posted by Jim Lewis on October 3rd, 2014

To emulate the process by which nature assembles complex organic molecules by passing subunits through a series of enzyme domains, UK chemists developed a procedure to elongate a boronic ester by using a reagent that inserts into carbon-boron bonds with precise control of molecular configuration.

Nanomanufacturing grants available from US National Science Foundation

Posted by Jim Lewis on September 27th, 2014

The US NSF has announced a program to support fundamental research leading to complex nanosystems.

Scaffolded DNA origami improvements advance DNA nanotechnology

Posted by Jim Lewis on September 25th, 2014

A 10-fold larger breadboard and 350-fold lower DNA synthesis costs make DNA origami a more useful stepping-stone toward atomically precise manufacturing.

What kind of nanomachines will advanced nanotechnology use?

Posted by Jim Lewis on August 31st, 2014

An interview with UK nanotechnologist Richard Jones argues that the surest and most efficient path to advanced nanomachine function will incorporate or mimic biomolecular nanomachinery rather than scaled down rigid conventional machinery.

Emergence of nanobiotechnology points to importance of deep collaboration

Posted by Jim Lewis on August 8th, 2014

Study shows more than 500 firms involved in nanobiotechnology, which is expected to soon triple in size. Research points to the importance of broad networks and deep collaborations.

Biotech lab in the cloud lowers entry barrier to nanotech research

Posted by Jim Lewis on August 5th, 2014

With biotech fundamental to several paths to advanced nanotechnology, a way to do biotech experiments in the cloud offers small groups the chance to quickly test their ideas.

Building biological molecular machines as an open source path to advanced nanotechnology

Posted by Jim Lewis on July 24th, 2014

B.R.AI.N.S., Berkeley BioLabs, and Foresight Institute to build an open source biological parts repository and design and distribute a line of “How-to Build Biological Machines” educational kits.