RNA CAD tools developed for RNA-regulated control of gene expression in synthetic biology successfully engineered metabolic pathways in bacteria. Will engineering RNA-based genetic control systems lead to design tools for other RNA-based molecular machine systems?
Archive for the 'Productive Nanosystems' Category
A tutorial review addresses the distinction between the many simple artificial molecular devices that are currently available and truly effective artificial molecular machines that would mimic the ubiquitous molecular machines present in living systems.
In a lecture at Oxford Eric Drexler argued that atomically precise manufacturing will be the next great revolution in the material basis of civilization, and discussed how we can establish reliable knowledge about key aspects of such technologies.
The oscillating synthesis and degradation of regulatory RNA molecules was used to produce a molecular clock to control the opening and closing of a DNA tweezers, and also to control the production of another RNA molecule to alter the fluorescence of a dye molecule.
Tiles made from DNA helices have been made to self-assemble into a more complex structure, which then was used to seed the formation of a complementary structure. This second structure in turn seeded the formation of multiple copies of the first structure.
Engineered bacteria that incorporate unnatural amino acids at multiple positions provide a new tool that may facilitate designing proteins to fold more predictably into molecular machinery components.
Ultrasound was used to pull on polymer chains attached to opposite sides of a chemically almost inert molecular ring, splitting it into its two components.
News articles by Jon Cartwright on the Chemistry World news site and by Michael Berger at Nanowerk describe a significant molecular machine milestone achieved by the research groups of David A. Leigh (winner of the 2007 Foresight Institute Feynman Prize in Nanotechnology for Theory) and Anne-Sophie Duwez. The research was reported in Nature Nanotechnology [abstract]. [...]
A green nanotechnology roadmap released by the American Chemical Society describes the opportunities and barriers to developing commercial applications of nanomaterials that present little threat of harm to health and the environment, and concludes with an action agenda to more forward.
Submit your own work or nominate a colleague for the 2011 Foresight Institute Feynman Prizes.
Will an inexpensive automated evolution machine accelerate the development of molecular machine systems by simultaneously evolving multiple parts to improve function?
New computational method screens for small molecules that bind to RNA molecules that move through a variety of conformations.
We’re going to take a shot at doing a live webcast of Foresight@Google: 25th Anniversary Conference and Celebration. See this page for schedule and link: http://foresight.org/reunion/schedule.html It’s free so please have patience if we run into any technical difficulties. You can try sending questions to speakers by using this Twitter tag (though in-person participants get first [...]
A new book collects the papers and discussions from the 2007 Solvay Conference “From Noncovalent Assemblies to Molecular Machines”.
I. Foresight@Google: Registration Deadline – Wed June 22nd II. Open Foresight Reception in Palo Alto – Friday June 24th III. Senior Associates Reunion Banquet – Saturday June 25th IV. Thiel Foundation’s 20Under20 to attend Foresight@Google ================================== I. Foresight@Google Registration Deadline – Wednesday June 22nd Foresight@Google – June 24-26, 2011 25th Anniversary Conference Celebration & Reunion Weekend [...]
Does the recent discovery that quantum tunneling controls a chemical reaction of a carbene complicate theoretical studies of nanotechnology, especially of diamond mechanosynthesis?
Computational studies show that small diamond structures of the type that might serve as nanoparts in diamondoid molecular machinery are structurally stable.
A biochemical circuit built from 74 small DNA molecules demonstrates an approach that may enable embedded control of molecular devices.
We are proud to announce our final conference program for Foresight@Google‘s 25th Anniversary Conference Celebration, held June 25-26 in Mountain View, CA. For $50 off registration use code: NANODOT This weekend – full of plenary talks, panels, and breakout sessions – is a unique opportunity to be stimulated, enlightened and inspired by direct interaction with [...]
A Monte-Carlo simulation shows that a simple self-replicating RNA-like molecule in a specific protective environment could evolve the ability to translate a genetic code to produce peptides.