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Archive for the 'Productive Nanosystems' Category

RNA CAD tool for synthetic biology may facilitate RNA nanotechnology

Posted by Jim Lewis on December 27th, 2011

RNA CAD tools developed for RNA-regulated control of gene expression in synthetic biology successfully engineered metabolic pathways in bacteria. Will engineering RNA-based genetic control systems lead to design tools for other RNA-based molecular machine systems?

Tutorial review of the promise of artificial molecular machines

Posted by Jim Lewis on December 11th, 2011

A tutorial review addresses the distinction between the many simple artificial molecular devices that are currently available and truly effective artificial molecular machines that would mimic the ubiquitous molecular machines present in living systems.

Lecture by Eric Drexler at Oxford on physical law and the future of nanotechnology (video)

Posted by Jim Lewis on December 6th, 2011

In a lecture at Oxford Eric Drexler argued that atomically precise manufacturing will be the next great revolution in the material basis of civilization, and discussed how we can establish reliable knowledge about key aspects of such technologies.

An artificial molecular clock to control artificial molecular machines

Posted by Jim Lewis on November 4th, 2011

The oscillating synthesis and degradation of regulatory RNA molecules was used to produce a molecular clock to control the opening and closing of a DNA tweezers, and also to control the production of another RNA molecule to alter the fluorescence of a dye molecule.

Self-replication achieved using structural DNA nanotechnology

Posted by Jim Lewis on October 26th, 2011

Tiles made from DNA helices have been made to self-assemble into a more complex structure, which then was used to seed the formation of a complementary structure. This second structure in turn seeded the formation of multiple copies of the first structure.

Engineered bacteria provide new tool for nanotechnology protein design

Posted by Jim Lewis on September 26th, 2011

Engineered bacteria that incorporate unnatural amino acids at multiple positions provide a new tool that may facilitate designing proteins to fold more predictably into molecular machinery components.

Mechanical force splits molecule that cannot otherwise be split

Posted by Jim Lewis on September 16th, 2011

Ultrasound was used to pull on polymer chains attached to opposite sides of a chemically almost inert molecular ring, splitting it into its two components.

First direct measurement of force generated by an individual synthetic molecular machine

Posted by Jim Lewis on August 29th, 2011

News articles by Jon Cartwright on the Chemistry World news site and by Michael Berger at Nanowerk describe a significant molecular machine milestone achieved by the research groups of David A. Leigh (winner of the 2007 Foresight Institute Feynman Prize in Nanotechnology for Theory) and Anne-Sophie Duwez. The research was reported in Nature Nanotechnology [abstract]. [...]

Green Nanotechnology Roadmap Highlights Opportunities and Challenges

Posted by Jim Lewis on August 23rd, 2011

A green nanotechnology roadmap released by the American Chemical Society describes the opportunities and barriers to developing commercial applications of nanomaterials that present little threat of harm to health and the environment, and concludes with an action agenda to more forward.

2011 Foresight Institute Feynman Prize deadline is September 30, 2011

Posted by Jim Lewis on July 25th, 2011

Submit your own work or nominate a colleague for the 2011 Foresight Institute Feynman Prizes.

An evolution machine to accelerate nanotechnology development?

Posted by Jim Lewis on July 8th, 2011

Will an inexpensive automated evolution machine accelerate the development of molecular machine systems by simultaneously evolving multiple parts to improve function?

Handling flexible parts in RNA nanotechnology

Posted by Jim Lewis on June 30th, 2011

New computational method screens for small molecules that bind to RNA molecules that move through a variety of conformations.

Free webcast this weekend of Foresight Conference at Google

Posted by Christine Peterson on June 23rd, 2011

We’re going to take a shot at doing a live webcast of Foresight@Google: 25th Anniversary Conference and Celebration. See this page for schedule and link: It’s free so please have patience if we run into any technical difficulties. You can try sending questions to speakers by using this Twitter tag (though in-person participants get first [...]

New book on molecular machines

Posted by Jim Lewis on June 20th, 2011

A new book collects the papers and discussions from the 2007 Solvay Conference “From Noncovalent Assemblies to Molecular Machines”.

Foresight 25th anniversary: Open reception June 24, SrAssoc banquet June 25

Posted by Christine Peterson on June 16th, 2011

I. Foresight@Google: Registration Deadline – Wed June 22nd II.  Open Foresight Reception in Palo Alto – Friday June 24th III. Senior Associates Reunion Banquet – Saturday June 25th IV. Thiel Foundation’s 20Under20 to attend Foresight@Google ================================== I. Foresight@Google Registration Deadline – Wednesday June 22nd Foresight@Google – June 24-26, 2011 25th Anniversary Conference Celebration & Reunion Weekend [...]

Does quantum tunneling complicate theoretical studies of nanotechnology?

Posted by Jim Lewis on June 16th, 2011

Does the recent discovery that quantum tunneling controls a chemical reaction of a carbene complicate theoretical studies of nanotechnology, especially of diamond mechanosynthesis?

Theoretical work establishes structural stability of nanoscale diamond structures

Posted by Jim Lewis on June 10th, 2011

Computational studies show that small diamond structures of the type that might serve as nanoparts in diamondoid molecular machinery are structurally stable.

Computational circuit built from 74 small DNA molecules (with video)

Posted by Jim Lewis on June 9th, 2011

A biochemical circuit built from 74 small DNA molecules demonstrates an approach that may enable embedded control of molecular devices.

Foresight@Google: Full Program of Speakers posted!

Posted by Christine Peterson on June 2nd, 2011

We are proud to announce our final conference program for Foresight@Google‘s 25th Anniversary Conference Celebration, held June 25-26 in Mountain View, CA.  For $50 off registration use code: NANODOT This weekend – full of plenary talks, panels, and breakout sessions – is a unique opportunity to be stimulated, enlightened and inspired by direct interaction with [...]

Computer simulation of evolution of primordial molecular machine

Posted by Jim Lewis on June 1st, 2011

A Monte-Carlo simulation shows that a simple self-replicating RNA-like molecule in a specific protective environment could evolve the ability to translate a genetic code to produce peptides.