Scaffolded DNA origami is combined with hinges of single- or double-stranded DNA to built simple machines parts that have been combined to program simple to complex motions.
Archive for the 'Future Medicine' Category
Combinations of different types of DNA nanorobots, implementing different logic gates, work together to tag a specific type of cell in a living cockroach depending on the presence or absence of two protein signals.
New software makes it possible to generate 3D structures of proteins without artificially incorporating metal atoms in the proteins, making it possible to study many molecular machines using data that could not previously be analyzed.
A more general computational framework predicts the structures of 2D and 3D-curved DNA nanostructures impossible to predict using previously available computational methods. May lead to 3D-printing DNA nanostructures?
Design principles have been developed and tested to construct novel synthetic protein monomers that can self-assemble into large, open protein cages for potential use in vaccines and drug delivery.
A nanoparticle that self-assembles from porphyrin, cholic acid, amino acids, and polyethylene glycol is a promising vehicle for delivering both imaging agents and cancer drugs to tumors.
Nicholas Negroponte, founder of the MIT media lab and the One Laptop Per Child program, gave a TED talk in March 2014 titled A 30-Year History of the Future. Click to access the talk or the TEDBlog article discussing the talk. Negroponte highlights some cutting-edge technological developments of the past that had been openly scorned [...]
Foresight friends can use this discount to attend the SENS Rejuvenation Biotechnology Conference August 21-23, 2014 Santa Clara, California.
Enveloped DNA nanostructures were developed to escape attacks from nucleases and the immune system, opening a path to ever more sophisticated DNA nanomedical devices.
The photos from the 2014 Foresight Technical Conference highlight entrepreneurial efforts in space, biotechnology, and life extension.
The complex molecular recognition code of RNA offers RNA nanotechnology a greater variety of 3D structures and functions than are present in DNA nanotechnology, but the RNA structures can be fragile. New RNA triangles that resist boiling solve this problem.
By targeting the protein that attaches a type of immune cell called neutrophils to blood vessel walls where they cause serious tissues damage, the neutrophils are released and returned to the circulation to resume their normal functions.
RNA interference provides potential cures for various diseases by silencing the expression of specific genes in specific organs, but delivering the RNA molecules to the right place is very difficult. A novel nanoparticle provides unprecedented efficiency in silencing target genes in liver cells.
The concern of the US GAO for a gap in nanomanufacturing is well-placed, but it is only half of the problem with the limited US vision of the impact of nanotechnology on the future world economy.
A new tool to chemically modify one specific carbon atom among several chemically very similar ones will facilitate building larger, more complex molecules for drug discovery and for nanotechnology.
A “sense of energy, momentum, and collegiality throughout the weekend” united attendees hearing about the integration of nano-engineered devices and materials into more complex systems, and the integration of nanoscale technologies into diverse applications.
A reconstituted high-density lipoprotein nanoparticle reduces inflammation in advanced atherosclerotic plaques in mice. Will it work in humans to prevent repeat heart attacks and stroke?
A recently released technology report titled Nano-solutions for the 21st century outlines nanotech-based solutions to global challenges. Several years in the making, the report was co-authored by Dennis Pamlin, Research Fellow at the Chinese Academy of Social Sciences Research Center for Sustainable Development (RCSD web site currently in Chinese only), and Eric Drexler, Academic Visitor [...]
A collection of open access journals on a variety of topics provides a very useful entry point to the rapidly growing collection of scientific, technical, and scholarly research that is not hidden behind pay walls.
A new book by Frank Boehm explores the challenges, possibilities, and visions of nanomedical device and systems design.