Scaffolded DNA origami is combined with hinges of single- or double-stranded DNA to built simple machines parts that have been combined to program simple to complex motions.
Archive for the 'Artificial Molecular Machines' Category
Among the smallest molecular robots reported so far, a walker based on phenylarsonous acid with two organic thiol ligands as feet walks through a one-nanometer-diameter protein nanopore channel by taking 0.6 nanometer steps, by thiol exchange, from one cysteine residue to the next.
A phosphorescent molecule is made to flap like a butterfly when absorbed light shortens the distance between two platinum atoms.
An interview with UK nanotechnologist Richard Jones argues that the surest and most efficient path to advanced nanomachine function will incorporate or mimic biomolecular nanomachinery rather than scaled down rigid conventional machinery.
Attaching a 200-nm-diameter magnetic bead to a 1-nm diameter synthetic molecular machine allowed optical visualization of the motion of the machine and manipulation with a magnetic tweezers.
Nanotech promises more commonplace access to advanced technology as material and fabrication costs fall and traditional barriers to innovation are removed. Examples are already being seen globally: more access to laptops and cell phones in developing countries, desktop 3D printers, a surge in establishment of shared-use research facilities, etc. A couple recent cases getting attention [...]
B.R.AI.N.S., Berkeley BioLabs, and Foresight Institute to build an open source biological parts repository and design and distribute a line of “How-to Build Biological Machines” educational kits.
A swinging DNA arm added to a DNA scaffold makes it possible for two enzymes attached to the scaffold to complete a coupled chemical reaction.
A possible top-down path to atomically precise manufacturing that passes through microscale machinery might be rendered easier because of recent progress in suppressing the Casimir force, which contributes to the ‘stiction’ problem often encountered with microelectromechanical systems.
A DNA clamp engineered for higher specificity and higher affinity may improve cancer diagnosis and treatment and may also mean better control over building nanomachines.
A possible forerunner to a future molecular assembly line uses an artificial DNA motor to transport an artificial nanoparticle along a carbon nanotube track.
A study of RNA structures actually present in cells reveals that cells spend energy restricting thermodynamically driven RNA folding so that fewer RNA structures are found in cells than in test tubes.
A collection of open access journals on a variety of topics provides a very useful entry point to the rapidly growing collection of scientific, technical, and scholarly research that is not hidden behind pay walls.
At the 2013 Conference Philip Moriarty presented non-contact Atomic Force Microscope experiments demonstrating mechanical toggling of silicon dimers on a silicon surface. The crucial role of precise control of probe tip structure was emphasized.
Using DNA nanotechnology to control and organize molecular motors and the molecular tracks that they run on, a novel nanotrain transports molecular cargos tens of micrometers.
Doug Wolens’s documentary “THE SINGULARITY: Will we survive our technology” premieres at San Francisco’s Castro Theatre September 16, 2013.
At the 2013 Conference the winner of the 2011 Feynman Prize for Experimental work presents STM studies showing how the manipulation of single molecules on a surface can yield insights to their mechanical, electronic, and optical properties, and be used in a controlled way to build pre-defined molecular architectures.
The Conference to be held February 7-9, 2014 in Palo Alto, California will emphasize the integration of nano-engineered devices and materials into larger, more complex systems.
Revolution of DNA around a central channel, rather than rotation, is the method used by a viral molecular motor to package DNA. A structure facilitating bottom-up assembly may lead to roles in nanotechnology for these nanomotors.
A small molecular machine based on a rotaxane molecule autonomously added three amino acids in a programmed order to a seed tripeptide to form a hexapeptide