A DNA clamp engineered for higher specificity and higher affinity may improve cancer diagnosis and treatment and may also mean better control over building nanomachines.
Archive for the 'Artificial Molecular Machines' Category
A possible forerunner to a future molecular assembly line uses an artificial DNA motor to transport an artificial nanoparticle along a carbon nanotube track.
A study of RNA structures actually present in cells reveals that cells spend energy restricting thermodynamically driven RNA folding so that fewer RNA structures are found in cells than in test tubes.
A collection of open access journals on a variety of topics provides a very useful entry point to the rapidly growing collection of scientific, technical, and scholarly research that is not hidden behind pay walls.
At the 2013 Conference Philip Moriarty presented non-contact Atomic Force Microscope experiments demonstrating mechanical toggling of silicon dimers on a silicon surface. The crucial role of precise control of probe tip structure was emphasized.
Using DNA nanotechnology to control and organize molecular motors and the molecular tracks that they run on, a novel nanotrain transports molecular cargos tens of micrometers.
Doug Wolens’s documentary “THE SINGULARITY: Will we survive our technology” premieres at San Francisco’s Castro Theatre September 16, 2013.
At the 2013 Conference the winner of the 2011 Feynman Prize for Experimental work presents STM studies showing how the manipulation of single molecules on a surface can yield insights to their mechanical, electronic, and optical properties, and be used in a controlled way to build pre-defined molecular architectures.
The Conference to be held February 7-9, 2014 in Palo Alto, California will emphasize the integration of nano-engineered devices and materials into larger, more complex systems.
Revolution of DNA around a central channel, rather than rotation, is the method used by a viral molecular motor to package DNA. A structure facilitating bottom-up assembly may lead to roles in nanotechnology for these nanomotors.
A small molecular machine based on a rotaxane molecule autonomously added three amino acids in a programmed order to a seed tripeptide to form a hexapeptide
Electrons from a scanning tunneling microscope tip turn a five-arm rotor connected via a single ruthenium atom bearing to a tripod anchoring the molecular motor to a gold surface.
One research group working with rotaxanes and another group working with carbon nanotubes have provided two very different solutions to the problem of producing motion via artificial muscles at different scales from the nano to the macro.
A study of a biological molecular machine has shown that the machine functions most effectively when it uses chemical bonds just barely strong enough to survive the power stroke of the machine.
A brief article reviews several types of molecular machines that chemists have built to mimic biology and provide movement for future types of nanotechnology.
The 2013 Foresight Technical Conference: Illuminating Atomic Precision will be held January 11-13, 2013 in Palo Alto, CA USA.
A theoretical study shows that although thermal noise cannot be used to produce useful motion by mesoscale or macroscale machines, it can be used by nanoscale machines without violating the second law of thermodynamics.
The demonstration that the process of DNA replication is more flexible than thought should make it easier to incorporate unusual amino acids into designed proteins, which might make it easier to design novel protein machines.
Darpa has launched a “Living Foundries” program to bring an engineering perspective to synthetic biology to greatly accelerate progress through standardization and modularization.
A set of rationally engineered transcriptional regulators for yeast will make it easier to build complex molecular machine systems in yeast, some of which may become useful additions to pathway technologies for atomically precise manufacturing and productive nanosystems.