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Archive for the 'Nanobiotechnology' Category

Nanoparticle therapy for incurable brain cancer effective in mice

Posted by Jim Lewis on November 15th, 2013

Gold nanoparticles densely coated with RNA molecules intended to silence a gene essential for an incurable brain cancer proved effective in mice engrafted with human glioblastoma multiforme tumor.

Adding more chemical interactions to DNA nanotechnology

Posted by Jim Lewis on October 24th, 2013

Modifying DNA strands with lipid-like molecules opens more possibilities for designing DNA structures for drug delivery and other purposes.

Computational design of protein-small molecule interactions

Posted by Jim Lewis on September 26th, 2013

A major advance in the computational design of proteins that bind tightly to specific small molecules will facilitate several technologies, possibly including the development of atomically precise manufacturing.

Building a hub for nanotech advancement

Posted by Stephanie C on September 17th, 2013

Nanotechnology draws from physics, chemistry, engineering, computation, etc., and this multi-disciplinary nature has served as a major speed bump in achievement of envisioned nanotech goals. There has been substantial concern that the U.S. is lagging behind other countries in nanotech R&D. Now researchers, companies, and politicians are coming together to create a much-needed physical hub [...]

Circuits of graphitic nanoribbons grown from aligned DNA templates

Posted by Jim Lewis on September 17th, 2013

How complex could circuits be made using precisely positioned DNA nanostructures as templates to grow graphene nanoribbons?

Precise mechanical manipulation of individual long DNA molecules

Posted by Jim Lewis on September 12th, 2013

“Molecular threading”, a nanotechnology developed by Halcyon Molecular and now owned by Aeon Biowares, enables precise placement of individual long molecules of DNA, either for sequencing or for nanofabrication of novel DNA nanostructures.

Next Foresight Conference on Nanotechnology in February 2014

Posted by Jim Lewis on August 28th, 2013

The Conference to be held February 7-9, 2014 in Palo Alto, California will emphasize the integration of nano-engineered devices and materials into larger, more complex systems.

Improved molecular targeting via cellular automata

Posted by Stephanie C on August 12th, 2013

In simplest terms, cellular automata can be thought of as groups of ‘cells’ in which the state of an individual cell will flip depending on the states of its neighbors. A ‘cell’ can be a pixel, a molecule, etc. The mathematical rules associated with cellular automation are complex and have been applied to fields as [...]

Nanoscale box aids single-molecule optical detection

Posted by Stephanie C on July 29th, 2013

Good old fashioned boxes are here to stay, even in the context of nanoscale devices. Across a broad range of technologies and size regimes, boxes serve as containers for components, barriers against contaminants and/or radiation, and, as in the case of cell membranes, can be permeable to allow selected interactions between the interior and exterior. [...]

DNA nanotechnology positions components to optimize single-molecule fluorescence

Posted by Jim Lewis on July 19th, 2013

A pillar constructed and positioned using DNA nanotechnology holds two gold nanoparticles and a dye molecule to enhance fluorescence over a hundred fold.

Reviews of DNA nanotechnology-atomically precise microscale objects

Posted by Jim Lewis on July 9th, 2013

Two open access reviews portray the widening approach of DNA nanotechnology toward more complex atomically precise systems.

DNA nanotechnology builds solar energy antenna

Posted by Jim Lewis on June 21st, 2013

A simple DNA scaffold organizes light-collecting molecules for artificial photosynthesis.

Mass production of higher quality oligonucleotides to spur DNA nanotechnology

Posted by Jim Lewis on June 6th, 2013

Biotechnology-based isolation and amplification of sequence-verified clones of DNA oligonucleotides will provide longer and less expensive materials for building complex DNA nanostructures and nanomachinery.

RNA-protein motor for unidirectional movement of DNA in nanomachinery

Posted by Jim Lewis on April 1st, 2013

Revolution of DNA around a central channel, rather than rotation, is the method used by a viral molecular motor to package DNA. A structure facilitating bottom-up assembly may lead to roles in nanotechnology for these nanomotors.

Nanotechnology revolution: An interview with Eric Drexler

Posted by Stephanie C on March 29th, 2013

In anticipation of Eric Drexler’s new book, Forbes contributor Bruce Dorminey interviews him about the meaning of nanotechnology and its revolutionary prospects. Selected excerpt: … In what fields would APM cause the most pronounced economic disruption and the collapse of global supply chains to more local chains? The digital revolution had far-reaching effects on information [...]

Re-engineering a junction to give a new twist to DNA nanotechnology

Posted by Jim Lewis on March 29th, 2013

By forcing the geometry of the junctions upon which DNA nanotechnology depends, researchers have increased the collection of 2D and 3D structures that they can build to include wire frames and mesh structures.

Computationally designed peptide sneaks nanoparticles past immune system

Posted by Jim Lewis on March 15th, 2013

Nanoparticles decorated to avoid immune system recognition were tested in mice and shown to survive longer and deliver more imaging dye and drug to tumor cells.

A teenager’s step toward nanomedicine innovation

Posted by Stephanie C on March 6th, 2013

In this Forbes interview, contributor John Nosta introduces us to a teen worth watching: fifteen-year-old Jack Andraka, whose effort to design a nanotube-based sensor for pancreatic cancer detection was initially ignored. The interview taps into some aspects of how innovation occurs and the challenges of bringing new ideas to fruition – aspects which transcend age, [...]

Proposed Brain Activity Map may also advance nanotechnology

Posted by Jim Lewis on March 1st, 2013

A proposed large project to produce a dynamic map of the functional connectome of the human brain will require a convergence of neuroscience, biotechnology, nanotechnology, and computation, and may therefore spur the development of advanced nanotechnology leading to molecular manufacturing.

Nanotechnology delivers potent anti-cancer agent where it needs to go

Posted by Jim Lewis on February 22nd, 2013

Core-shell nanocapsules deliver a potent protein complex to the nucleus of cancer cells where it induces them to commit suicide, while the complex degrades harmlessly in the cytoplasm of normal cells.