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Archive for the 'Nanobiotechnology' Category

Leveraging nanoforces to increase biosensor sensitivity

Posted by Jim Lewis on November 16th, 2011

This contribution has been forwarded by Ivo Rivetta. The primary forces on the nanometer scale are scaled versions of what we experience on a day to day basis. Instead of gravity, surface forces such as water tension and electric charge dominate. As an example, compare wet basketballs and wet sand. The weight of the basketballs [...]

An artificial molecular clock to control artificial molecular machines

Posted by Jim Lewis on November 4th, 2011

The oscillating synthesis and degradation of regulatory RNA molecules was used to produce a molecular clock to control the opening and closing of a DNA tweezers, and also to control the production of another RNA molecule to alter the fluorescence of a dye molecule.

Carbon nanotube muscles could propel future medical nanorobots (video)

Posted by Jim Lewis on October 31st, 2011

Yarn woven from carbon nanotubes provides a thousand times more rotation than is obtained from other artificial muscles, and could be made into motors to provide propulsion for micrometer-sized medical nanorobots.

Using DNA as bonds to build new materials from nanoparticles

Posted by Jim Lewis on October 31st, 2011

Varying the length of the DNA used to connect the nanoparticles provides for a wide variety of nanoparticle sizes and crystal symmetries.

Viruses guide nano-assembly of biomaterials

Posted by Jim Lewis on October 27th, 2011

This contribution has been forwarded by Ivo Rivetta. Researchers at UC Berkeley have taken a bioinspired approach to control the nanostructure of deposited thin films. In living organisms, the orientation of collagen in tissue determines its properties: For instance, a number of blue-skinned animals, including the mandrill monkey, derive their coloring not from pigment, but [...]

Self-replication achieved using structural DNA nanotechnology

Posted by Jim Lewis on October 26th, 2011

Tiles made from DNA helices have been made to self-assemble into a more complex structure, which then was used to seed the formation of a complementary structure. This second structure in turn seeded the formation of multiple copies of the first structure.

Destroying cancer cells by incorporating an artificial biological computer

Posted by Jim Lewis on October 14th, 2011

A complex piece of DNA that acts as a biological computer when it is inserted into cells determines whether or not the cell is a specific type of cancer cell, and if so, initiates the suicide of that cell.

Magnetic nanoparticles to cook brain cancer go into trial in patient

Posted by Jim Lewis on October 12th, 2011

Nanotechnology has been applied to produce various types of nanoparticles that can deliver toxic agents specifically to the cancer cells. Many of these approaches have shown promise in animal studies. One approach using magnetic nanoparticles has now gone into trials in patients. From “Nano-therapy that cooks deadly brain tumors advances in Germany,” by Ryan McBride: [...]

Nanotechnology using designed peptides to build supramolecular structures on surfaces

Posted by Jim Lewis on September 29th, 2011

An algorithm helps design peptides that will self-assemble on a given surface to produce a supramolecular structure of desired geometry.

Nanotechnology for Heart Repair Advances

Posted by Jim Lewis on September 29th, 2011

Growing heart cells in a scaffold containing gold nanowires produces a tissue patch that is thicker and in which the cells beat synchronously as they do in healthy heart tissue.

Engineered bacteria provide new tool for nanotechnology protein design

Posted by Jim Lewis on September 26th, 2011

Engineered bacteria that incorporate unnatural amino acids at multiple positions provide a new tool that may facilitate designing proteins to fold more predictably into molecular machinery components.

Bio-Nanomachinery Dinner Lecture, Mountain View, CA, August 30

Posted by Jim Lewis on August 23rd, 2011

Have you seen those beautiful animations illustrating how the complex molecular machinery in a cell works? (Ex. http://youtu.be/sa563MdIiXE) Just how much of that is ‘made up’? How much is real? How is the information gathered, and what potentials can we unlock with it? Foresight is proud to announce its next dinner lecture: “Elucidating Bio-Nanomachines: Microscopies [...]

Molecular information theory points to robust molecular communications

Posted by Jim Lewis on August 4th, 2011

Those interested in issues of communication at the nanoscale will be interested to learn that the first volume of the new journal Nano Communication Networks, from Elsevier, edited by Ian Akyildiz, is available free of charge. The volume comprises four issues dated March through December of 2010. Just to pick one article out of dozens [...]

A four-artificial-neuron network from 112 DNA strands

Posted by Jim Lewis on July 22nd, 2011

A neural network made from 112 DNA strands organized into four artificial neurons was trained with four pieces of information to answer questions.

DNA nanotechnology provides detailed monitoring of single cells

Posted by Jim Lewis on July 19th, 2011

DNA nanotechnology provides cell-surface sensors for real-time monitoring of single cells, including potential use in personalized medicine to test which drugs would be suitable for which individuals.

Nanotechnology therapy for head and neck cancer shows promise

Posted by Jim Lewis on July 15th, 2011

A nanotechnology therapy using targeted dendrimers shows promise against head and neck cancer in experiments in which human tumors are implanted into immunocompromised mice.

First synthetic organ transplant made possible by nanotechnology

Posted by Jim Lewis on July 11th, 2011

The world’s first synthetic organ transplant was a replica windpipe made from a nanocomposite scaffold seeded with the patient’s own adult stem cells.

An evolution machine to accelerate nanotechnology development?

Posted by Jim Lewis on July 8th, 2011

Will an inexpensive automated evolution machine accelerate the development of molecular machine systems by simultaneously evolving multiple parts to improve function?

Handling flexible parts in RNA nanotechnology

Posted by Jim Lewis on June 30th, 2011

New computational method screens for small molecules that bind to RNA molecules that move through a variety of conformations.

Free webcast this weekend of Foresight Conference at Google

Posted by Christine Peterson on June 23rd, 2011

We’re going to take a shot at doing a live webcast of Foresight@Google: 25th Anniversary Conference and Celebration. See this page for schedule and link: http://foresight.org/reunion/schedule.html It’s free so please have patience if we run into any technical difficulties. You can try sending questions to speakers by using this Twitter tag (though in-person participants get first [...]