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Archive for the 'Nanobiotechnology' Category

Nanotechnology greatly improves sensitivity of common medical tests

Posted by Jim Lewis on June 21st, 2012

A new nanomaterial provides a three million-fold improvement in the sensitivity of common medical tests, potentially permitting earlier detection of cancer and Alzheimer’s disease.

New method to identify intermediates in protein folding

Posted by Jim Lewis on June 12th, 2012

Tryptophan residues introduced at various positions in a protein chain identify folding intermediates that are too short-lived to be structurally characterized otherwise.

Advancing nanotechnology with protein building blocks

Posted by Jim Lewis on June 6th, 2012

A variety of protein cage structures have been constructed by designing specific protein domains to self-assemble as atomically precise protein building blocks in defined geometries.

DNA tiles provide faster, less expensive way to fabricate complex DNA objects

Posted by Jim Lewis on May 31st, 2012

A set of 310 short single-stranded DNA tiles, plus a few additional short sequences for the edges, has been used to form more than a hundred large, complex DNA objects.

New Darpa program may accelerate synthetic biology path to advanced nanotechnology

Posted by Jim Lewis on May 26th, 2012

Darpa has launched a “Living Foundries” program to bring an engineering perspective to synthetic biology to greatly accelerate progress through standardization and modularization.

Foresight Presents: “GENOGEN: Regenerating Skin for Life”, with Dr. Nancy Mize

Posted by Jim Lewis on May 20th, 2012

Nancy K Mize, PhD, Scientist, Innovator, and CEO of GENOGEN Inc., will continue Foresight’s local Bay Area community events with a lecture “GENOGEN: Regenerating Skin for Life”. GENOGEN is developing products that activate resident skin stem cells to stimulate local areas of regeneration of skin naturally – the way children heal.

Drug-resistant cancer cells cannot resist plasmonic nanobubbles

Posted by Jim Lewis on May 13th, 2012

Nanoparticles targeted to cancer cells by antibodies cannot achieve enough specificity to kill drug-resistant cancer cells while sparing normal cells, but can achieve enough specificity to produce nanobubbles only in cancer cells, so the drug only enters cancer cells.

Foresight Institute on Singularity Hub (video)

Posted by Jim Lewis on May 12th, 2012

Recent interview touches on new Foresight programs and issues in nanotechnology development

Gold nanostars shuttled to cancer cell nucleus to release drug

Posted by Jim Lewis on April 24th, 2012

Gold nanostars targeted to a protein over-expressed in most cancer cells are shuttled by that protein directly to the cancer cell nucleus where illumination with a laser light releases a drug that deforms the nucleus and kills the cell.

Nanoparticles reduce tumors in clinical trial

Posted by Jim Lewis on April 17th, 2012

Clinical trials in patients with advanced or metastatic tumors using targeted nanoparticles to deliver a standard chemotherapeutic drug showed tumor shrinkage, even in the case of cancers for which that drug is not normally effective.

Adding to the toolbox for making complex molecular machines

Posted by Jim Lewis on April 4th, 2012

A set of rationally engineered transcriptional regulators for yeast will make it easier to build complex molecular machine systems in yeast, some of which may become useful additions to pathway technologies for atomically precise manufacturing and productive nanosystems.

Nanotechnology-based sensor does rapid reads of single DNA molecule

Posted by Jim Lewis on April 1st, 2012

A combination of a molecular motor protein and a nanopore protein has been harnessed for rapidly sequencing single DNA molecules.

Nanotechnology regrows blood vessels after ischemic damage

Posted by Jim Lewis on March 26th, 2012

In a rat model of ischemic damage, nanoparticle delivery of a growth factor and a coreceptor promotes regrowth of damaged blood vessels in seven days.

Faster, less expensive medical diagnostics through nanotechnology

Posted by Jim Lewis on March 23rd, 2012

New protein repellent coating enhances the speed of carbon nanotube-based biosensors, pointing the way to faster, cheaper medical diagnostics.

DNA nanotechnology-based nanorobot delivers cell suicide message to cancer cells

Posted by Jim Lewis on March 8th, 2012

Functioning DNA nanorobots to deliver specific molecular signals to cells were designed by combining DNA origami, DNA aptamers, and DNA logic gates.

Nanotechnology, digital fabrication, and innovation at TED

Posted by Jim Lewis on March 2nd, 2012

A talk at TEDxBerkeley includes nanotechnology among the options for digital fabrication, one of five new rules of innovation.

Novel RNA structural motifs expand tool kit for RNA nanotechnology

Posted by Jim Lewis on February 26th, 2012

New computational methods to explore the rapidly expanding collection of high resolution three-dimensional RNA structures reveal new RNA structural motifs, identifying additional building blocks for complex RNA nanostructures.

Nanotechnology, DNA sequencing, and personalized medicine

Posted by Jim Lewis on February 20th, 2012

Artist’s conception of a nanopore drilled into a layer of graphene to speed up DNA sequencing. One of the greatest promises of near-term nanotechnoloogy is cheaper DNA sequencing to speed the development of personalized medicine. There are not only genetic differences between different patients, but also genetic differences between, for example, different cancers of the [...]

DNA motor navigates network of DNA tracks

Posted by Jim Lewis on January 31st, 2012

Scientists at Kyoto University and the University of Oxford have combined DNA origami and DNA motors to take another step toward programmed artificial molecular assembly lines.

Crowd-sourced protein design a promising path to advanced nanotechnology

Posted by Jim Lewis on January 24th, 2012

Foldit game players have again out-performed scientists in protein design, this time improving the design of a protein designed from scratch to catalyze Diels-Alder cycloadditions.