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Archive for the 'Nanobiotechnology' Category

Foresight Institute on Singularity Hub (video)

Posted by Jim Lewis on May 12th, 2012

Recent interview touches on new Foresight programs and issues in nanotechnology development

Gold nanostars shuttled to cancer cell nucleus to release drug

Posted by Jim Lewis on April 24th, 2012

Gold nanostars targeted to a protein over-expressed in most cancer cells are shuttled by that protein directly to the cancer cell nucleus where illumination with a laser light releases a drug that deforms the nucleus and kills the cell.

Nanoparticles reduce tumors in clinical trial

Posted by Jim Lewis on April 17th, 2012

Clinical trials in patients with advanced or metastatic tumors using targeted nanoparticles to deliver a standard chemotherapeutic drug showed tumor shrinkage, even in the case of cancers for which that drug is not normally effective.

Adding to the toolbox for making complex molecular machines

Posted by Jim Lewis on April 4th, 2012

A set of rationally engineered transcriptional regulators for yeast will make it easier to build complex molecular machine systems in yeast, some of which may become useful additions to pathway technologies for atomically precise manufacturing and productive nanosystems.

Nanotechnology-based sensor does rapid reads of single DNA molecule

Posted by Jim Lewis on April 1st, 2012

A combination of a molecular motor protein and a nanopore protein has been harnessed for rapidly sequencing single DNA molecules.

Nanotechnology regrows blood vessels after ischemic damage

Posted by Jim Lewis on March 26th, 2012

In a rat model of ischemic damage, nanoparticle delivery of a growth factor and a coreceptor promotes regrowth of damaged blood vessels in seven days.

Faster, less expensive medical diagnostics through nanotechnology

Posted by Jim Lewis on March 23rd, 2012

New protein repellent coating enhances the speed of carbon nanotube-based biosensors, pointing the way to faster, cheaper medical diagnostics.

DNA nanotechnology-based nanorobot delivers cell suicide message to cancer cells

Posted by Jim Lewis on March 8th, 2012

Functioning DNA nanorobots to deliver specific molecular signals to cells were designed by combining DNA origami, DNA aptamers, and DNA logic gates.

Nanotechnology, digital fabrication, and innovation at TED

Posted by Jim Lewis on March 2nd, 2012

A talk at TEDxBerkeley includes nanotechnology among the options for digital fabrication, one of five new rules of innovation.

Novel RNA structural motifs expand tool kit for RNA nanotechnology

Posted by Jim Lewis on February 26th, 2012

New computational methods to explore the rapidly expanding collection of high resolution three-dimensional RNA structures reveal new RNA structural motifs, identifying additional building blocks for complex RNA nanostructures.

Nanotechnology, DNA sequencing, and personalized medicine

Posted by Jim Lewis on February 20th, 2012

Artist’s conception of a nanopore drilled into a layer of graphene to speed up DNA sequencing. One of the greatest promises of near-term nanotechnoloogy is cheaper DNA sequencing to speed the development of personalized medicine. There are not only genetic differences between different patients, but also genetic differences between, for example, different cancers of the [...]

DNA motor navigates network of DNA tracks

Posted by Jim Lewis on January 31st, 2012

Scientists at Kyoto University and the University of Oxford have combined DNA origami and DNA motors to take another step toward programmed artificial molecular assembly lines.

Crowd-sourced protein design a promising path to advanced nanotechnology

Posted by Jim Lewis on January 24th, 2012

Foldit game players have again out-performed scientists in protein design, this time improving the design of a protein designed from scratch to catalyze Diels-Alder cycloadditions.

Advanced nanofactories in twenty years?

Posted by Jim Lewis on January 12th, 2012

An article in The Guardian quotes Christine Peterson and Robert Freitas on the vision of molecular manufacturing. Freitas is quoted as expecting that the development of nanofactories could be done in 20 years for “on the order of” one billion dollars.

First Master's of Science in Nanomedicine degree program in US announced

Posted by Jim Lewis on January 6th, 2012

The first Master’s of Science in Nanomedicine degree program in US is announced. As an example of the rapidly developing potential of nanomedicine, a novel type of nanoparticle succeeded in two different mouse models in destroying a type of brain cancer that had previously been completely resistant to all treatment attempts.

Arrays of artificial molecular machines could lead to atomically precise nanotechnology

Posted by Jim Lewis on December 29th, 2011

A tutorial review available after free registration presents a theory-based exploration of the difficulty in moving from simple molecular switches to arrays of artificial molecular machines capable to doing substantial, useful external work.

RNA CAD tool for synthetic biology may facilitate RNA nanotechnology

Posted by Jim Lewis on December 27th, 2011

RNA CAD tools developed for RNA-regulated control of gene expression in synthetic biology successfully engineered metabolic pathways in bacteria. Will engineering RNA-based genetic control systems lead to design tools for other RNA-based molecular machine systems?

Mechanical pressure produces atomically-precise, multifunctional 2D sheets

Posted by Jim Lewis on December 26th, 2011

Protein-like structures called peptoids can be formed into stable, free-floating nanosheets.

Christine Peterson on current state and future potential of nanotechnology

Posted by Jim Lewis on December 21st, 2011

When can we expect advanced nanomachinery to be commercialized? Will any technologies not be affected in some way by advanced nanotechnology?

Tutorial review of the promise of artificial molecular machines

Posted by Jim Lewis on December 11th, 2011

A tutorial review addresses the distinction between the many simple artificial molecular devices that are currently available and truly effective artificial molecular machines that would mimic the ubiquitous molecular machines present in living systems.