A new DARPA program seeks to bridge the gap from atoms to macroscale product manufacture in two steps, the first of which is from atoms to micrometer-scale feedstocks. DNA origami may be part of the solution.
Archive for the 'Molecular manufacturing' Category
A 10-fold larger breadboard and 350-fold lower DNA synthesis costs make DNA origami a more useful stepping-stone toward atomically precise manufacturing.
Swiss researchers have used biomolecular shuttles to capture molecular building blocks from solution and transport them across fluid flow boundaries to be further manipulated in a subsequent chamber.
Register by Sept. 5 to attend a Proposers Day webinar on either Sept. 9 or 11 to learn the technical objectives of DARPA’s new “Atoms to product: Aiming to make nanoscale benefits life-sized” program.
An interview with UK nanotechnologist Richard Jones argues that the surest and most efficient path to advanced nanomachine function will incorporate or mimic biomolecular nanomachinery rather than scaled down rigid conventional machinery.
Attaching a 200-nm-diameter magnetic bead to a 1-nm diameter synthetic molecular machine allowed optical visualization of the motion of the machine and manipulation with a magnetic tweezers.
Rice University’s breakthrough nanoporous silicon oxide technology for resistive random-access memory (RRAM) appears poised for commercialization.
Study shows more than 500 firms involved in nanobiotechnology, which is expected to soon triple in size. Research points to the importance of broad networks and deep collaborations.
With biotech fundamental to several paths to advanced nanotechnology, a way to do biotech experiments in the cloud offers small groups the chance to quickly test their ideas.
B.R.AI.N.S., Berkeley BioLabs, and Foresight Institute to build an open source biological parts repository and design and distribute a line of “How-to Build Biological Machines” educational kits.
Enveloped DNA nanostructures were developed to escape attacks from nucleases and the immune system, opening a path to ever more sophisticated DNA nanomedical devices.
The complex molecular recognition code of RNA offers RNA nanotechnology a greater variety of 3D structures and functions than are present in DNA nanotechnology, but the RNA structures can be fragile. New RNA triangles that resist boiling solve this problem.
A swinging DNA arm added to a DNA scaffold makes it possible for two enzymes attached to the scaffold to complete a coupled chemical reaction.
A bacterium has been engineered to stably propagate a DNA written with six letters instead of the usual four, greatly expanding the number of amino acids, both natural and synthetic, that can be genetically encoded. Further work could lead to novel proteins incorporating these additional amino acids, and from there to novel materials, devices, and machines.
Reviewing Eric Drexler’s Radical Abundance, Phil Bowermaster provides an informed and insightful overview of the controversies that greeted the proposal for a nanotechnology aimed at developing a practical technology for atomically precise manufacturing. Along the way he shows how Drexler’s outlook evolved from 1986 to 2013.
A possible top-down path to atomically precise manufacturing that passes through microscale machinery might be rendered easier because of recent progress in suppressing the Casimir force, which contributes to the ‘stiction’ problem often encountered with microelectromechanical systems.
The concern of the US GAO for a gap in nanomanufacturing is well-placed, but it is only half of the problem with the limited US vision of the impact of nanotechnology on the future world economy.
Using struts made of DNA to stiffen polyhedral corners, scientists have build rigid DNA cages an order of magnitude larger than previous DNA nanostructures, and only one order of magnitude smaller than bacterial cells.
A new tool to chemically modify one specific carbon atom among several chemically very similar ones will facilitate building larger, more complex molecules for drug discovery and for nanotechnology.
A “sense of energy, momentum, and collegiality throughout the weekend” united attendees hearing about the integration of nano-engineered devices and materials into more complex systems, and the integration of nanoscale technologies into diverse applications.