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Archive for the 'Nanotechnology' Category

Overview of molecular machines documents recent progress

Posted by Jim Lewis on September 4th, 2015

A review of molecular parts that act as switches, motors, and ratchets illuminates similarities between artificial and biological molecular machines and argues that useful applications are coming.

Nanotechnology provides sensors for liver-on-chip drug testing

Posted by Jim Lewis on September 2nd, 2015

Adding nanotechnology-based optoelectronic sensors to human cells cultured on a chip keeps the cells healthy long enough to replace animal testing with a human liver-on-a-chip.

Femtosecond imaging with near nanometer spatial resolution

Posted by Jim Lewis on August 31st, 2015

Analysis of multiple diffraction images provides high contrast, high quality, full field 3D imaging of surfaces illuminated by extreme ultraviolet photons from a tabletop laser.

A tunable bandgap by doping a few atomic layers of black phosphorous

Posted by Jim Lewis on August 29th, 2015

A vertical electrical field from dopant atoms of potassium added to the surface of a few stacked layers of phosphorene tunes the band gap of black phosphorous, possibly leading to novel electronic and optoelectronic devices.

Novel wireframe nanostructures from new DNA origami design process

Posted by Jim Lewis on August 18th, 2015

A new set of design rules enables constructing any wireframe nanostructure, which may lead to new medical applications and new nanomachines.

Conference video: Artificial Biochemistry with DNA

Posted by Jim Lewis on August 13th, 2015

Modeling DNA strand displacement cascades according to three simple rules can in principle mimic the temporal dynamics of any other chemical system, presenting a method to model regulatory networks even more complicated than those of biology.

Another nanotechnology computer memory breakthrough from Feynman Prize winner

Posted by Jim Lewis on August 12th, 2015

A novel nanostructured material based on tantalum oxide could make possible non-volatile crossbar array memories that store up to 162 gigabits in 3-D memory stacks.

Ribosome subunits tethered to make versatile artificial molecular machine

Posted by Jim Lewis on August 11th, 2015

Functional ribosomes with subunits engineered to not separate at the completion of each protein translation cycle make possible engineering systems to make a variety of novel polymers with novel properties.

Automated design of polyhedral meshes for DNA origami

Posted by Jim Lewis on August 7th, 2015

An automated design process folds arbitrary meshes to produce DNA origami structures difficult to design by previous methods, including more open structures that are stable in ionic conditions used in biological assays.

Arranging molecular chromophores on DNA brick nanobreadboards

Posted by Jim Lewis on August 6th, 2015

Nanobreadboards made of DNA bricks provide twice the positional precision, twice the packing density, and faster prototyping than do alternative means to arrange functional molecules.

Facilitating structural DNA nanotechnology with non-aqueous solvents

Posted by Jim Lewis on August 2nd, 2015

Recent research demonstrates that certain non-aqueous solvents can not only be used to assemble DNA nanostructures, but offer certain advantages over conventional aqueous solvents.

Foresight co-sponsors Berkeley Bench to Market event

Posted by Jim Lewis on July 30th, 2015

To educate potential entrepreneurs on strategies for moving discoveries from the benchtop to successful commercialization, Foresight co-sponsored an event in the “Ph.D. to Startup” Workshop Series of the Berkeley Postdoc Entrepreneur Program.

Foresight 1999 Distinguished Student wins Galactic Grant Competition

Posted by Jim Lewis on July 28th, 2015

Technology developed by Nanobiosym, founded by Anita Goel, to enable personalized diagnostic testing won the Grand Prize of the Nokia Sensing XCHALLENGE in 2013, and this month was awarded the top prize in the Galactic Grant Competition.

Conference video: Conformational and compositional dynamics of a molecular machine

Posted by Jim Lewis on July 8th, 2015

At the 2013 Conference Joseph Puglisi described how single molecule fluorescence techniques were used to study changes in the conformation and composition of the ribosome, a large biomolecular nanomachine, during the process of translation of genetic information.

Linking together small DNAs to build more diverse DNA nanostructures

Posted by Jim Lewis on July 2nd, 2015

Using the enzyme DNA ligase and small DNA strands as building blocks provides an efficient and less expensive path to a large variety of DNA scaffolds and other structures.

Toward advanced nanotechnology: Working solid state molecular shuttle

Posted by Jim Lewis on July 1st, 2015

A molecular ring shuttles back and forth between two positions on a molecular axle held rigidly inside a solid state molecular lattice made from a metal organic framework.

Wafer-scale atomically precise thin layers for nanotechnology

Posted by Jim Lewis on June 30th, 2015

By precise control of several factors, uniform high-performance monolayers of the semiconductor MoS2 have been obtained and used to fabricate field-effect transistors.

DNA nanomachines more stable than expected in human serum and blood

Posted by Jim Lewis on June 29th, 2015

Even without special designs and coatings to promote stability, simple DNA nanomachines can survive in human serum and blood for hours or even days, much longer than expected from previous studies using bovine serum, which has more damaging nucleases than does human serum.

Google Tech Talk video by Feynman Prize Winner

Posted by Jim Lewis on June 24th, 2015

Designing and building spiroligomers, robust building blocks of various 3D shapes made from unnatural amino acids, decorated with various functional groups, and linked rigidly together by pairs of bonds, and a new approach to nanotechnology design software.

US OSTP seeking suggestions for Nanotechnology Grand Challenges

Posted by Jim Lewis on June 23rd, 2015

A US government Request for Information (RFI) is seeking suggestions for Nanotechnology-Inspired Grand Challenges for the Next Decade. The manufacture of atomically-precise materials is offered as #4 of 6 examples.