Computational design of an enzyme that carboligates three one-carbon molecules to form one three-carbon molecule, an activity that does not exist in nature, provides proof-of-principle for a novel metabolic pathway for carbon fixation.
Archive for the 'Nanotechnology' Category
A nanoengine 100 times more powerful than known nanomotors and muscles was demonstrated using the aggregation and dispersal of gold nanoparticles coated with a polymer that undergoes a rapid transition from hydrophobic to hydrophilic.
Christine Peterson will speak on “High-Leverage Altruism” at the fourth annual conference of Effective Altruism, using reason and evidence to improve the world as much as possible, and on nanotechnology at the Singularity University Global Summit, the definitive gathering for those who understand the critical importance of exponential technologies.
Foresight President Julia Bossmann will speak on AI at the TEDxEchoPark “Paradigm Shift” event on Saturday May 14, 2016, in Los Angeles, California.
A DNA strand capable of forming a triple helix with a portion of the DNA double helices in a macroscopic DNA crystal enhances the weak interactions holding the crystal together so that the crystal remains stable in the absence of a high ionic strength environment.
A specially designed triplex forming oligonucleotide bearing a cargo molecule binds to a specific sequence in the major groove of a DNA double helix to form a modified DNA tile that self assembles into a macroscopic crystal in which each helix carries a cargo molecule positioned to sub-nanometer precision.
Structural DNA nanotechnology: progress toward a precise self-assembling three dimensional scaffold by building macroscopic crystals from nanoscale structures.
Five calcium ions held several micrometers apart in an ion trap and manipulated by laser pulses implement Shor’s factorization algorithm more efficiently than previous implementations.
Small, stiff, rectangular rods made using scaffolded DNA origami bypass drug resistance mechanisms in the membranes of a cultured leukemia cell line and release enough therapeutic drug to kill the cancer cell.
Increasing efficiency and utilization and lowering costs for harvesting, converting, transporting, and storing energy produced from sunlight provides a showcase for a variety of nanoscale materials, structures, and processes.
California Institute of Technology is holding a symposium to honor Paul Rothemund’s seminal contribution to the field of DNA nanotechnology: the research paths opened by the technology, and where they might lead.
Thousands of amateurs playing the online RNA folding game Eterna, backed up by a real-world automated lab testing their predictions, have provided insights to improve the algorithms computers use to design RNA molecules.
Do sophisticated medical applications of 3D printing, like printing titanium bones or human tissues, that portend wider use, also perhaps point toward eventual nanoscale applications as the technology improves?
A rotor with DNA origami parts held together by an engineered tight fit instead of by covalent bonds can revolve freely, driven by Brownian motion and dwelling at engineered docking sites.
Two research teams present two different methods for using single strands of DNA to link various nanoparticles into complex 3D arrays: one using DNA hairpins for dynamic reconfiguration and the other using a DNA origami scaffold.
A paradigm shift in analyzing diffraction from smaller, less perfect crystals yields improved resolution and enables directly determining the phase of the diffraction pattern.
Encapsulating enzymes in nanocages engineered using structural DNA nanotechnology increases enzymatic digestion and protects enzymes from degradation.
Polymer chemistry and materials research provide opportunities to explore structures that harmonize phenomena unique to nanoscale technology, the role of mechanical forces generated at interfaces, and the responses of biological systems to mechanical stresses.
New families of protein structures, barrel proteins for positioning small molecules, self-assembling protein arrays, and precision sculpting of protein architectures highlight de novo protein design advances.
Computational design of proteins satisfying predetermined geometric constraints produced stable proteins with the designed structure that are not found in nature.