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Archive for the 'Nano' Category

Foresight co-sponsors Berkeley Bench to Market event

Posted by Jim Lewis on July 30th, 2015

To educate potential entrepreneurs on strategies for moving discoveries from the benchtop to successful commercialization, Foresight co-sponsored an event in the “Ph.D. to Startup” Workshop Series of the Berkeley Postdoc Entrepreneur Program.

Foresight 1999 Distinguished Student wins Galactic Grant Competition

Posted by Jim Lewis on July 28th, 2015

Technology developed by Nanobiosym, founded by Anita Goel, to enable personalized diagnostic testing won the Grand Prize of the Nokia Sensing XCHALLENGE in 2013, and this month was awarded the top prize in the Galactic Grant Competition.

Conference video: Conformational and compositional dynamics of a molecular machine

Posted by Jim Lewis on July 8th, 2015

At the 2013 Conference Joseph Puglisi described how single molecule fluorescence techniques were used to study changes in the conformation and composition of the ribosome, a large biomolecular nanomachine, during the process of translation of genetic information.

Linking together small DNAs to build more diverse DNA nanostructures

Posted by Jim Lewis on July 2nd, 2015

Using the enzyme DNA ligase and small DNA strands as building blocks provides an efficient and less expensive path to a large variety of DNA scaffolds and other structures.

Toward advanced nanotechnology: Working solid state molecular shuttle

Posted by Jim Lewis on July 1st, 2015

A molecular ring shuttles back and forth between two positions on a molecular axle held rigidly inside a solid state molecular lattice made from a metal organic framework.

Wafer-scale atomically precise thin layers for nanotechnology

Posted by Jim Lewis on June 30th, 2015

By precise control of several factors, uniform high-performance monolayers of the semiconductor MoS2 have been obtained and used to fabricate field-effect transistors.

DNA nanomachines more stable than expected in human serum and blood

Posted by Jim Lewis on June 29th, 2015

Even without special designs and coatings to promote stability, simple DNA nanomachines can survive in human serum and blood for hours or even days, much longer than expected from previous studies using bovine serum, which has more damaging nucleases than does human serum.

Self-assembly of silicon metamaterial for nanoscale reflectors

Posted by Stephanie C on June 25th, 2015

Recently highlighted in a C&EN article titled Simple Process Creates Near-Perfect Mirrors Out of a Metamaterial, researchers out of Vanderbilt University developed a method to self-assemble silicon nanostructures to achieve highly (Bragg-like) reflective mirrors which capitalize on nanoscale properties not present in bulk structures. The self-assembly method is far simpler than previous, conventional electron beam [...]

Google Tech Talk video by Feynman Prize Winner

Posted by Jim Lewis on June 24th, 2015

Designing and building spiroligomers, robust building blocks of various 3D shapes made from unnatural amino acids, decorated with various functional groups, and linked rigidly together by pairs of bonds, and a new approach to nanotechnology design software.

US OSTP seeking suggestions for Nanotechnology Grand Challenges

Posted by Jim Lewis on June 23rd, 2015

A US government Request for Information (RFI) is seeking suggestions for Nanotechnology-Inspired Grand Challenges for the Next Decade. The manufacture of atomically-precise materials is offered as #4 of 6 examples.

Conference video: Regenesis: Bionano

Posted by Jim Lewis on June 9th, 2015

At the 2013 Conference George Church presented an overview of his work in developing applications of atomically precise nanotechnology intended for commercialization, from data storage to medical nanorobots to genomic sequencing to genomic engineering to mapping individual neuronal functioning in whole brains.

Computational nanotechnology reveals complex interactions in double-walled carbon nanotubes

Posted by Jim Lewis on June 8th, 2015

Density functional theory calculations of the electronic properties of double-walled carbon nanotubes (DWCNTs) comprising two concentric zigzag tubes of different chiralities reveal complex effects upon the electronic band gap, identifying candidate combinations for diverse applications from transistors to macroscopic conducting wires.

Arrays of pure semiconducting carbon nanotubes for nanoelectronics

Posted by Jim Lewis on June 6th, 2015

A very efficient and scalable method of completely removing metallic carbon nanotubes from mixtures of metallic and semiconducting carbon nanotubes produces arrays suitable for many applications and for studies of thin film transistors.

Dynamic nanomachines for DNA nanotechnology inspired by proteins

Posted by Jim Lewis on June 4th, 2015

Programmed assembly and disassembly of rigid 3D DNA origami objects has been achieved by designing complementary surface shapes based upon weak stacking interactions to create simple nanomachines.

Preserving protein function in DNA-protein nanostructures

Posted by Jim Lewis on June 1st, 2015

Linking proteins to DNA scaffolds to produce complex functional nanostructures can require chemistry that damages protein function. A new systematic approach avoids exposing proteins to damaging conditions.

Single molecule pump concentrates small molecules

Posted by Jim Lewis on May 26th, 2015

A rotaxane-based single molecule pump combines cycling oxidation-reduction potential of the solution with kinetic barriers to moving backward to concentrate small ring molecules against an energy gradient.

Conference video: Microscopic Reversibility: The Organizing Principle for Molecular Machines

Posted by Jim Lewis on May 13th, 2015

At the 2013 Conference Dean Astumian contrasted macroscopic machines at static equilibrium and molecular machines at dynamic equilibrium, and presented information ratchets and microscopic reversibility as the organizing principle of molecular machines.

Conference video: Multi-Million Atom Simulations for Single Atom Transistor Structures

Posted by Jim Lewis on May 12th, 2015

At the 2013 Conference Gerhard Klimeck presented the work of his computational nanotechnology network modeling nanoelectronic devices, using simulations of multi-million atom domains to understand the function of single atom devices embedded in larger nanostructures.

Nanoparticles shepherd DNA into cells to regulate immune response

Posted by Jim Lewis on May 6th, 2015

DNA sequences designed to either stimulate a specific immune response or to down-regulate an undesirable response deliver superior performance when organized on nanoparticles to reach their intended cellular targets.

Nanowires and bacteria harnessed for artificial photosynthesis

Posted by Jim Lewis on May 4th, 2015

A prototype system to produce chemicals and fuels from sequestered carbon dioxide, water, and sunlight uses semiconductor nanowires to produce electron-hole pairs, which are then used by two types of bacteria to produce oxygen and a variety of useful chemical products.