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Archive for the 'Nanomedicine' Category

To fight inflammation nanoparticles turn 'naughty' neutrophils into 'nice' neutrophils

Posted by Jim Lewis on May 1st, 2014

By targeting the protein that attaches a type of immune cell called neutrophils to blood vessel walls where they cause serious tissues damage, the neutrophils are released and returned to the circulation to resume their normal functions.

Novel nanoparticle efficiently silences gene expression in liver cells

Posted by Jim Lewis on April 29th, 2014

RNA interference provides potential cures for various diseases by silencing the expression of specific genes in specific organs, but delivering the RNA molecules to the right place is very difficult. A novel nanoparticle provides unprecedented efficiency in silencing target genes in liver cells.

US government report highlights flaws in US nanotechnology effort

Posted by Jim Lewis on April 1st, 2014

The concern of the US GAO for a gap in nanomanufacturing is well-placed, but it is only half of the problem with the limited US vision of the impact of nanotechnology on the future world economy.

Notes on 2014 Foresight nanotechnology conference

Posted by Jim Lewis on March 7th, 2014

A “sense of energy, momentum, and collegiality throughout the weekend” united attendees hearing about the integration of nano-engineered devices and materials into more complex systems, and the integration of nanoscale technologies into diverse applications.

In mice, nanoparticle reduces inflammation in atherosclerotic plaques

Posted by Jim Lewis on March 5th, 2014

A reconstituted high-density lipoprotein nanoparticle reduces inflammation in advanced atherosclerotic plaques in mice. Will it work in humans to prevent repeat heart attacks and stroke?

Better nanoswitches by integrating double and triple strand DNA

Posted by Jim Lewis on January 28th, 2014

A DNA clamp engineered for higher specificity and higher affinity may improve cancer diagnosis and treatment and may also mean better control over building nanomachines.

Open Access journals for nanotechnology and other topics

Posted by Jim Lewis on December 19th, 2013

A collection of open access journals on a variety of topics provides a very useful entry point to the rapidly growing collection of scientific, technical, and scholarly research that is not hidden behind pay walls.

Upcoming Book Explores Nanomedical Device and Systems Design

Posted by Jim Lewis on November 21st, 2013

A new book by Frank Boehm explores the challenges, possibilities, and visions of nanomedical device and systems design.

Graphene nanoribbon senses passage of individual bases of DNA

Posted by Jim Lewis on November 19th, 2013

A nanoribbon transistor no thicker than the distance between adjacent DNA bases provides high resolution sensing of DNA passage through nanopores, perhaps leading eventually to rapid DNA sequencing.

Nanoparticle therapy for incurable brain cancer effective in mice

Posted by Jim Lewis on November 15th, 2013

Gold nanoparticles densely coated with RNA molecules intended to silence a gene essential for an incurable brain cancer proved effective in mice engrafted with human glioblastoma multiforme tumor.

Adding more chemical interactions to DNA nanotechnology

Posted by Jim Lewis on October 24th, 2013

Modifying DNA strands with lipid-like molecules opens more possibilities for designing DNA structures for drug delivery and other purposes.

Precise mechanical manipulation of individual long DNA molecules

Posted by Jim Lewis on September 12th, 2013

“Molecular threading”, a nanotechnology developed by Halcyon Molecular and now owned by Aeon Biowares, enables precise placement of individual long molecules of DNA, either for sequencing or for nanofabrication of novel DNA nanostructures.

THE SINGULARITY film premiere at The Castro Theatre 09.16.13

Posted by Jim Lewis on September 6th, 2013

Doug Wolens’s documentary “THE SINGULARITY: Will we survive our technology” premieres at San Francisco’s Castro Theatre September 16, 2013.

Next Foresight Conference on Nanotechnology in February 2014

Posted by Jim Lewis on August 28th, 2013

The Conference to be held February 7-9, 2014 in Palo Alto, California will emphasize the integration of nano-engineered devices and materials into larger, more complex systems.

Improved molecular targeting via cellular automata

Posted by Stephanie C on August 12th, 2013

In simplest terms, cellular automata can be thought of as groups of ‘cells’ in which the state of an individual cell will flip depending on the states of its neighbors. A ‘cell’ can be a pixel, a molecule, etc. The mathematical rules associated with cellular automation are complex and have been applied to fields as [...]

Nanoscale box aids single-molecule optical detection

Posted by Stephanie C on July 29th, 2013

Good old fashioned boxes are here to stay, even in the context of nanoscale devices. Across a broad range of technologies and size regimes, boxes serve as containers for components, barriers against contaminants and/or radiation, and, as in the case of cell membranes, can be permeable to allow selected interactions between the interior and exterior. [...]

Drexler's book tour extends to U.S. May6-9

Posted by Stephanie C on May 4th, 2013

Recently we pointed at a Forbe’s interview with Eric Drexler, in anticipation of his pending new book Radical Abundance. The book  has shipped, and Drexler’s tour schedule now includes a few stops on the coasts of the U.S: New York: May 6th Los Angeles: May 8th & 9th Seattle: May 9th Find exact times and [...]

RNA-protein motor for unidirectional movement of DNA in nanomachinery

Posted by Jim Lewis on April 1st, 2013

Revolution of DNA around a central channel, rather than rotation, is the method used by a viral molecular motor to package DNA. A structure facilitating bottom-up assembly may lead to roles in nanotechnology for these nanomotors.

Nanotechnology revolution: An interview with Eric Drexler

Posted by Stephanie C on March 29th, 2013

In anticipation of Eric Drexler’s new book, Forbes contributor Bruce Dorminey interviews him about the meaning of nanotechnology and its revolutionary prospects. Selected excerpt: … In what fields would APM cause the most pronounced economic disruption and the collapse of global supply chains to more local chains? The digital revolution had far-reaching effects on information [...]

Computationally designed peptide sneaks nanoparticles past immune system

Posted by Jim Lewis on March 15th, 2013

Nanoparticles decorated to avoid immune system recognition were tested in mice and shown to survive longer and deliver more imaging dye and drug to tumor cells.