A very large community of online gamers has consistently produced RNA designs that outperform the best design algorithms by a large margin. Can online gamers designing RNA, protein, and other molecules contribute to the development of atomically precise manufacturing?
Archive for the 'Atomically Precise Manufacturing (APM)' Category
A DNA clamp engineered for higher specificity and higher affinity may improve cancer diagnosis and treatment and may also mean better control over building nanomachines.
A possible forerunner to a future molecular assembly line uses an artificial DNA motor to transport an artificial nanoparticle along a carbon nanotube track.
A study of RNA structures actually present in cells reveals that cells spend energy restricting thermodynamically driven RNA folding so that fewer RNA structures are found in cells than in test tubes.
A recently released technology report titled Nano-solutions for the 21st century outlines nanotech-based solutions to global challenges. Several years in the making, the report was co-authored by Dennis Pamlin, Research Fellow at the Chinese Academy of Social Sciences Research Center for Sustainable Development (RCSD web site currently in Chinese only), and Eric Drexler, Academic Visitor [...]
A collection of open access journals on a variety of topics provides a very useful entry point to the rapidly growing collection of scientific, technical, and scholarly research that is not hidden behind pay walls.
Design and prediction are integral to Atomically Precise Manufacturing and its development. This is in part because fully functional APM can be readily explored computationally today, to levels of precision that cannot be experimentally developed today. In such a context, design is not just a resource but an approach. With rapidly expanding computational power, examples [...]
At the 2013 Conference Philip Moriarty presented non-contact Atomic Force Microscope experiments demonstrating mechanical toggling of silicon dimers on a silicon surface. The crucial role of precise control of probe tip structure was emphasized.
Using DNA nanotechnology to control and organize molecular motors and the molecular tracks that they run on, a novel nanotrain transports molecular cargos tens of micrometers.
A new book by Frank Boehm explores the challenges, possibilities, and visions of nanomedical device and systems design.
Modifying DNA strands with lipid-like molecules opens more possibilities for designing DNA structures for drug delivery and other purposes.
Eric Drexler’s TEDx talk entitled “A Future of Radical Abundance: Transforming the Material Basis of Civilization” is available for viewing on Youtube as well as on Drexler’s blog site. As described by the Oxford Martin School, where Drexler is a scholar with the Programme on the Impacts of Future Technology: Dr. Eric Drexler’s talk from [...]
A major advance in the computational design of proteins that bind tightly to specific small molecules will facilitate several technologies, possibly including the development of atomically precise manufacturing.
“Molecular threading”, a nanotechnology developed by Halcyon Molecular and now owned by Aeon Biowares, enables precise placement of individual long molecules of DNA, either for sequencing or for nanofabrication of novel DNA nanostructures.
Doug Wolens’s documentary “THE SINGULARITY: Will we survive our technology” premieres at San Francisco’s Castro Theatre September 16, 2013.
At the 2013 Conference the winner of the 2011 Feynman Prize for Experimental work presents STM studies showing how the manipulation of single molecules on a surface can yield insights to their mechanical, electronic, and optical properties, and be used in a controlled way to build pre-defined molecular architectures.
The Conference to be held February 7-9, 2014 in Palo Alto, California will emphasize the integration of nano-engineered devices and materials into larger, more complex systems.
Graphene molecules a bit more than one nanometer across and greatly distorted from planarity have altered properties and offer novel building blocks for nanotechnology.
A limited set of videos from the January 2013 Foresight Conference have been made available. John Randall started the Conference presentations describing the patterned silicon Atomic Layer Epitaxy (ALE) approach to atomically precise manufacturing.
A pillar constructed and positioned using DNA nanotechnology holds two gold nanoparticles and a dye molecule to enhance fluorescence over a hundred fold.