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Archive for the 'Atomically Precise Manufacturing (APM)' Category

Chirality-assisted synthesis a new tool for nanotechnology

Posted by Jim Lewis on October 30th, 2015

A novel application of supramolecular chemistry allows molecules to join in only one direction, providing a new way to control the shape of large molecules.

Surface assisted self-assembly of DNA origami nanostructures

Posted by Jim Lewis on October 26th, 2015

A lipid bilayer supported by a mica surface assisted the mobile self-assembly of DNA nanostructures of various shapes into micrometer-scale 2D lattices.

Free online edition of The Feynman Lectures on Physics

Posted by Jim Lewis on October 25th, 2015

A free to read online edition of the classic 3-volume physics text developed from Richard Feynman’s legendary Cal Tech physics lectures, specially designed for online reading, has been made available by the California Institute of Technology and the Feynman Lectures Website.

Foresight co-founder on the future of the human lifespan

Posted by Jim Lewis on October 6th, 2015

Optimized Geek podcast featured Christine Peterson on the future of nanotechnology, human lifespan, artificial intelligence, finding love, and other topics.

Atomically precise boron doping of graphene nanoribbons

Posted by Jim Lewis on September 28th, 2015

The ability to dope graphene nanoribbons with boron atoms to atomic precision opens a range of possible new applications, from chemical sensing to nanoelectronics to photocatalysis to battery electrodes.

Addressable molecular machines arranged in a porous crystal

Posted by Jim Lewis on September 10th, 2015

Simple molecular switches based upon bistable mechanically interlocked molecules can be incorporated within pre-assembled metal organic frameworks and addressed electrochemically.

Conference video: Artificial Biochemistry with DNA

Posted by Jim Lewis on August 13th, 2015

Modeling DNA strand displacement cascades according to three simple rules can in principle mimic the temporal dynamics of any other chemical system, presenting a method to model regulatory networks even more complicated than those of biology.

Automated design of polyhedral meshes for DNA origami

Posted by Jim Lewis on August 7th, 2015

An automated design process folds arbitrary meshes to produce DNA origami structures difficult to design by previous methods, including more open structures that are stable in ionic conditions used in biological assays.

Arranging molecular chromophores on DNA brick nanobreadboards

Posted by Jim Lewis on August 6th, 2015

Nanobreadboards made of DNA bricks provide twice the positional precision, twice the packing density, and faster prototyping than do alternative means to arrange functional molecules.

Facilitating structural DNA nanotechnology with non-aqueous solvents

Posted by Jim Lewis on August 2nd, 2015

Recent research demonstrates that certain non-aqueous solvents can not only be used to assemble DNA nanostructures, but offer certain advantages over conventional aqueous solvents.

Conference video: Conformational and compositional dynamics of a molecular machine

Posted by Jim Lewis on July 8th, 2015

At the 2013 Conference Joseph Puglisi described how single molecule fluorescence techniques were used to study changes in the conformation and composition of the ribosome, a large biomolecular nanomachine, during the process of translation of genetic information.

Wafer-scale atomically precise thin layers for nanotechnology

Posted by Jim Lewis on June 30th, 2015

By precise control of several factors, uniform high-performance monolayers of the semiconductor MoS2 have been obtained and used to fabricate field-effect transistors.

Google Tech Talk video by Feynman Prize Winner

Posted by Jim Lewis on June 24th, 2015

Designing and building spiroligomers, robust building blocks of various 3D shapes made from unnatural amino acids, decorated with various functional groups, and linked rigidly together by pairs of bonds, and a new approach to nanotechnology design software.

US OSTP seeking suggestions for Nanotechnology Grand Challenges

Posted by Jim Lewis on June 23rd, 2015

A US government Request for Information (RFI) is seeking suggestions for Nanotechnology-Inspired Grand Challenges for the Next Decade. The manufacture of atomically-precise materials is offered as #4 of 6 examples.

Conference video: Regenesis: Bionano

Posted by Jim Lewis on June 9th, 2015

At the 2013 Conference George Church presented an overview of his work in developing applications of atomically precise nanotechnology intended for commercialization, from data storage to medical nanorobots to genomic sequencing to genomic engineering to mapping individual neuronal functioning in whole brains.

Computational nanotechnology to benefit from expanded first-principles molecular dynamics

Posted by Jim Lewis on June 7th, 2015

A combination of techniques has made possible the expansion of problems that can be handled by first-principles molecular dynamics from a few hundred atoms to a very large system containing 32,768 atoms.

Preserving protein function in DNA-protein nanostructures

Posted by Jim Lewis on June 1st, 2015

Linking proteins to DNA scaffolds to produce complex functional nanostructures can require chemistry that damages protein function. A new systematic approach avoids exposing proteins to damaging conditions.

Single molecule pump concentrates small molecules

Posted by Jim Lewis on May 26th, 2015

A rotaxane-based single molecule pump combines cycling oxidation-reduction potential of the solution with kinetic barriers to moving backward to concentrate small ring molecules against an energy gradient.

Science and technology roadmaps for nanotechnology

Posted by Jim Lewis on May 3rd, 2015

A European Science and Technology Roadmap for Graphene, Related Two-Dimensional Crystals, and Hybrid Systems hints at the opportunities to be harvested from, and the need for, the development of atomically precise manufacturing (APM).

Foresight Institute Awards Feynman Prizes in Nanotechnology to Amanda S. Barnard, Joseph W. Lyding

Posted by Jim Lewis on April 23rd, 2015

The Theory Prize was given for research into diamond nanoparticles; the Experimental Prize was given for development of scanning tunneling microscope (STM) technology.