Ionized air means ozone, yes? Find me an electronics packaging engineer who wants you blowing ozone over their polymer based packages and adhesives. Not to mention dangers of possibly doping surface features on a chip due to high gradients of ions at the chip/air interface. Plus, moving ions sounds alot like moving electrons, i.e. current. What about the I^2R heat generation from the nanolightning? Oh, and RF interference from the electrostatic discharge? I'll bet if you put a noise source close enough to an RF chip, the power levels of the noise don't need to be very high at all.