As our knowledge on today over the matters of nature is limited, it may be inappropriate for us to analyze whether the benefits of Nanoscience outweigh its risks or not. As for as the nano-scale material development is concerned, so far there is no direct environmental risks can be predicted and the risk is only due to our inability to integrate its distributed developments and the unavailability of appropriate portals for the dissemination of its utilities, which may have socio-economic impacts on the globe. Yet, the mysterious depth of nanoscience cannot be predicted and the regulatory-reformations may be considered as spontaneous.