(From http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6931268&p_grant_num=1PN1EY016586-01&p_query=&ticket=11438445&p_audit_session_id=52354243&p_keywords= )

“Our goats are to apply complementary sets of nanotools towards learning how biological systems respond to physical cues, and to develop new technologies from the insights derived.”

If you don’t know how to do something, maybe a goat does…I guess this is just a different version of “If you want something done, forbid your child from doing it.” Or have they just got our goat?

But seriously, having looked at a few of the links, some of the nanomachines of interest are plain old holoenzymes and enzyme complexes.