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UCSD physicists model 100,000-atom nanopore reading DNA

From New Scientist, we learn of the modeling by UCSD physicists of 100,000 atoms to test the design of a silicon nitride nanopore reading DNA 200 times faster than doable today:

“The system could process the human genome in hours, researchers claim, compared with the 6 months it would take in today’s best labs.

” ‘Because we’re all physicists working on this we’ve started at the very bottom – with atoms,’ explains Johan Lagerqvist, a physicist at the University of California, San Diego, US, who worked on the simulation. Lagerqvist and colleagues tested a virtual version of the system by modelling how 100,000 atoms in a short DNA strand, the silicon nitride nanopore, its electrodes and the surrounding chemical solution would all interact.” There’s a 19.5 MB MPEG movie.

Meanwhile, the Harvard Nanopore Group led by Daniel Branton is attempting to build a similar nanopore. (Source: FUTUREdition) —Christine

2 Responses to “UCSD physicists model 100,000-atom nanopore reading DNA”

  1. Zelah Says:

    Here is a link to the paper:

  2. Nanodot: Nanotechnology News and Discussion » Blog Archive » Nanotechnology patents delayed, nanotech public understanding mixed Says:

    [...] We don’t usually like to link to subscription sites, but as an editorial advisory board member, I’ll make an exception for Nanotech Briefs (you can download a free sample). The August issue has the usual hard-core technical news: SiGe transistor operates at frequencies above 500 GHz, Method creates hollow nanocrystals, nanopore technique sequences DNA [note: despite the headline, this is a computer model, not a physical experimental result, though it sounds as though the latter may be getting close], Bacterial detection using quantum dot nanocomplexes, Miniature airborne-particle-mass monitors, Dot-in-well quantum dot photodetectors. [...]

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